6-(4-Ethoxybenzyl)-3-(phenylamino)-1,2,4-triazin-5(4H)-one CAS 905797-96-8

Purity 97%+In StockPharmaceutical Standards
CAS No.905797-96-8
Molecular FormulaC18H18N4O2
Molecular Weight322.36 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-(4-Ethoxybenzyl)-3-(phenylamino)-1,2,4-triazin-5(4H)-one CAS 905797-96-8 chemical structure

Description

The occurrence of 6-(4-Ethoxybenzyl)-3-(phenylamino)-1,2,4-triazin-5(4H)-one is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

6-(4-Ethoxybenzyl)-3-(phenylamino)-1,2,4-triazin-5(4H)-one (CAS 905797-96-8), molecular formula C18H18N4O2 and molecular weight 322.36 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 6-(4-Ethoxybenzyl)-3-(phenylamino)-1,2,4-triazin-5(4H)-one (C18H18N4O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 6-(4-Ethoxybenzyl)-3-(phenylamino)-1,2,4-triazin-5(4H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H18N4O2
Molecular Weight322.36 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Nitrogen Atoms4

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