6-Chloro-2-(4-chlorophenyl)-3-methylquinoline-4-carboxylic acid CAS 906143-01-9
| CAS No. | 906143-01-9 |
| Molecular Formula | C17H11Cl2NO2 |
| Molecular Weight | 332.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-Chloro-2-(4-chlorophenyl)-3-methylquinoline-4-carboxylic acid (CAS 906143-01-9), molecular formula C17H11Cl2NO2 and molecular weight 332.18 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Chloro-2-(4-chlorophenyl)-3-methylquinoline-4-carboxylic acid (C17H11Cl2NO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures 6-Chloro-2-(4-chlorophenyl)-3-methylquinoline-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H11Cl2NO2 |
| Molecular Weight | 332.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 6-Chloro-2-(2-methoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-29-5)
- 6-Chloro-2-(3-methoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-30-8)
- 6-Chloro-2-(4-methoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-31-9)
- 8-Chloro-2-(4-methoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-65-9)
- 8-Chloro-2-(3-methoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-67-1)
- 8-Chloro-2-(2-methoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-69-3)
- 3-Acetyl-6-chloro-4-(4-chlorophenyl)quinolin-2(1H)-one (CAS 1283108-77-9)
- (2E)-3-(3-Chloro-4-methoxyphenyl)-2-[(E)-2-chlorobenzoyl]prop-2-enenitrile (CAS 861207-91-2)
Recommended Standards
- 6-Chloro-2-(3-chlorophenyl)-3-methylquinoline-4-carboxylic acid (CAS 886361-68-8)
- 6-Chloro-2-(4-chlorophenyl)quinoline-4-carbohydrazide (CAS 590360-17-1)
- 5-(2-Chlorophenyl)-N-(4-chlorophenyl)furan-2-carboxamide (CAS 199458-91-8)
- 7-Chloro-2-(2-chlorophenyl)-8-methylquinoline-4-carboxylic acid (CAS 725221-35-2)
- tert-Butyl 4-cyano-4-(4-fluorobenzyl)piperidine-1-carboxylate (CAS 894769-77-8)
- 2-Amino-3-(3-bromothiophen-2-yl)propanamide (CAS 1485732-03-3)
- 2-[2-(2-Nitrophenoxy)ethyl]piperidinehydrochloride (CAS 1219982-53-2)
- ((2S,3S,4R,5R)-3-(benzoyloxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,4-difluorotetrahydrofuran-2-yl)methyl benzoate (CAS 1612841-23-2)
- 1-methyl-1H,2H,3H-pyrrolo[2,3-c]pyridin-2-one (CAS 161563-35-5)
- 1-(4-Bromophenyl)-3-methylcyclopent-3-enamine (CAS 1822679-97-9)
- 2-Cyclohexylacetonitrile (CAS 4435-14-7)
- tert-Butyl 4-(2-ethoxyethylamino)piperidine-1-carboxylate (CAS 1154374-52-3)
- 3-{[(4-methylphenyl)methyl]sulfanyl}-5H-[1,2,4]triazino[5,6-b]indole (CAS 332166-81-1)
- Ac-(5-31)Semaglutide (CAS CATO-C4X-2226279)
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