Ceftizoxime Impurity 12 CAS 90712-49-5

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ceftizoxime Impurity 12.

CATO supplies Ceftizoxime Impurity 12 (CAS 90712-49-5), a pharmacopoeial impurity reference standard (molecular formula C7H8N2O3S, MW 200.22 g/mol) used for the identification and quantification of trace impurities in APIs.

Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Ceftizoxime Impurity 12 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 200.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Ceftizoxime Impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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