4-(4-Methoxyphenyl)-2-(methylthio)-6-phenylnicotinonitrile CAS 90745-12-3
| CAS No. | 90745-12-3 |
| Molecular Formula | C20H16N2OS |
| Molecular Weight | 332.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(4-Methoxyphenyl)-2-(methylthio)-6-phenylnicotinonitrile (CAS 90745-12-3) is a high-purity analytical reference standard with the molecular formula C20H16N2OS and a molecular weight of 332.42 g/mol.
4-(4-Methoxyphenyl)-2-(methylthio)-6-phenylnicotinonitrile (C20H16N2OS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H16N2OS |
| Molecular Weight | 332.42 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 4-(3-Methanesulfonyl-4-methyl-6-phenylpyridin-2-yl)morpholine (CAS 339017-11-7)
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- 3-(Methoxymethyl)-5-[(2-oxo-2-pyrrolidin-1-ylethyl)thio]-4-phenyl-4H-1,2,4-triazole (CAS 881595-76-2)
- 3-((6-Bromopyridin-2-yl)amino)propanoic acid (CAS 68638-67-5)
- 2-(1-(3,4-Dichlorophenyl)ethyl)-6-methyl-4,5-dihydropyridazin-3(2H)-one (CAS 70646-67-2)
- Methyl dodeca-3,6-dienoate (CAS 16106-01-7)
- 3-CARBAMOYL-4-FLUOROBENZOIC ACID (CAS 1534121-96-4)
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- Methyl 4-methoxybenzo[b]thiophene-2-carboxylate (CAS 146137-88-4)
- 1-Methyl-2-nitro-4-(trifluoromethoxy)benzene (CAS 70692-45-4)
- 5,6,7,8,9,10-Hexahydroimidazo[1,2-a]azocine (CAS 59521-37-8)
- [2,2':6',2''-Terpyridine]-6,6''-dicarboxylicacid (CAS 149982-11-6)
- Semaglutide Impurity 3 (CAS CATO-C4X-22263)
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