8-Chloro-2-(vinylthio)quinolin-3-ol CAS 90785-93-6
| CAS No. | 90785-93-6 |
| Molecular Formula | C11H8ClNOS |
| Molecular Weight | 237.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
8-Chloro-2-(vinylthio)quinolin-3-ol (CAS 90785-93-6) is a high-purity analytical reference standard with the molecular formula C11H8ClNOS and a molecular weight of 237.71 g/mol.
The molecular framework of 8-Chloro-2-(vinylthio)quinolin-3-ol (C11H8ClNOS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H8ClNOS |
| Molecular Weight | 237.71 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 5-Chloro-3-(methylthio)-6-phenyl-1,2,4-triazine (CAS 109307-01-9)
- 5-Chloro-N-ethyl-1,3-dimethyl-1H-pyrazole-4-sulfonamide (CAS 1215580-89-4)
- 2-Chloro-6,7-dihydrothieno[2',3':4,5]oxepino[3,2-b]pyridine (CAS 1282528-87-3)
- 4-Chloro-1-(2-(ethylsulfonyl)ethyl)-1h-pyrazol-3-amine (CAS 1342027-87-5)
- 5-((6-Chloro-3-pyridinyl)sulfanyl)-2-pyridinamine, 97% (CAS 1450622-58-8)
- n-(4-Chloro-1-ethyl-3-methyl-1h-pyrazol-5-yl)methanesulfonamide (CAS 1484641-23-7)
- 2-Chloro-7-methylsulfanyl-quinoline-3-carbaldehyde (CAS 73568-30-6)
- 4-Chloro-6-(phenylthio)pyrimidin-2-amine (CAS 339016-06-7)
Recommended Standards
- 5-Chloro-N,N,1,3-tetramethyl-1H-pyrazole-4-sulfonamide (CAS 88398-94-1)
- N-Denitroso-N'-nitroso Lomustine-d4 (CAS 1346603-97-1)
- 4-Methyl-2-phenyl-1,3-thiazole-5-carbonyl chloride (CAS 54001-18-2)
- tert-Butyl ((2R,3R)-4-chloro-3-hydroxy-3-methylbutan-2-yl)carbamate (CAS 2883819-42-7)
- 1-(3-methyl-1,2-oxazol-5-yl)cyclopropane-1-carboxylic acid (CAS 1469286-26-7)
- 5-(3-Acetylphenyl)-picolinic acid (CAS 1242339-32-7)
- 2-Amino-4,5-dimethylbenzo[d]thiazole (CAS 1065074-59-0)
- tert-Butyl N-butyl-N-(3-chlorophenyl)carbamate (CAS 1881293-18-0)
- 14-Hydroxy-3-methoxy-17-methyl-6-oxo-4-phenoxy-morphinan 6-Ethylene Ketal (1.0mg/ml in Acetonitrile) (CAS 21020-34-8)
- tert-Butyl (5-bromo-7-fluoro-1H-indol-3-yl)carbamate (CAS 2758501-37-8)
- 5-Bromo-1,2-dihydropyrimidin-2-one hydrobromide (CAS 81590-30-9)
- (R)-1-(3-Bromobenzyl)pyrrolidin-3-amine dihydrochloride (CAS 1349702-39-1)
- 2-{3,5-dimethyl-1-[3-(trifluoromethyl)phenyl]-1h-pyrazol-4-yl}-2-oxoacetic acid (CAS 875156-74-4)
- Acetyl-Tau Peptide (244-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 2022956-56-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com