N-Fmoc-6-fluoro-L-tryptophan CAS 908847-01-8
| CAS No. | 908847-01-8 |
| Molecular Formula | C26H21FN2O4 |
| Molecular Weight | 444.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of N-Fmoc-6-fluoro-L-tryptophan (C26H21FN2O4) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
N-Fmoc-6-fluoro-L-tryptophan (CAS 908847-01-8), molecular formula C26H21FN2O4 and molecular weight 444.45 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-Fmoc-6-fluoro-L-tryptophan meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H21FN2O4 |
| Molecular Weight | 444.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- Fmoc-5-fluoro-DL-tryptophan (CAS 138775-55-0)
- Fmoc-Trp(4-F)-OH (CAS 2244532-65-6)
- Fmoc-Gly-Phe-OH (CAS 117370-45-3)
- Fmoc-phenylalanyl-glycine (CAS 169624-67-3)
- Fmoc-L-Gln(Ph)-OH (CAS 198134-12-2)
- Fmoc-β-Ala-Phg-OH (CAS 2171258-99-2)
- Fmoc-beta-(benzothiazol-2-yl)-L-alanine (CAS 959583-56-3)
- Fmoc-DL-4-tert-butyl-Phe (CAS 1236257-38-7)
Recommended Standards
- Methyl 1,4-Dihydro-2,6-dimethyl-4-(2-trifluoromethyl)phenyl-pyridine-5-carboxylate-3-phenylmethyl Carboxamide (CAS 887407-01-4)
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(5-fluoro-1H-indol-3-yl)propanoic acid (CAS 908846-88-8)
- Z-Asp(OtBu)-ONp (CAS 17543-17-8)
- 6-(Bis(4-methoxybenzyl)amino)-4-methyl-3-(trifluoromethyl)picolinaldehyde (CAS 2812580-23-5)
- 5-Cyclopropyl-4-ethyl-4H-1,2,4-triazole-3-thiol (CAS 443918-29-4)
- [1-(Pyrrolidin-1-ylmethyl)cyclopropyl]-amine dihydrochloride (CAS 1401426-09-2)
- (1-Isopropyl-1H-pyrazol-4-yl)methanamine (CAS 936940-09-9)
- 2-Keto-3-(methyl-d<SUB>3</SUB>)-butyric acid-1,2,3,4-<SUP>13</SUP>C<SUB>4</SUB> sodium salt (CAS 1215605-14-3)
- Sodium 1,1-dioxidotetrahydrothiophen-3-yl sulfate (CAS 479485-98-8)
- methyl 2-(cyclobutylamino)benzoate (CAS 1247084-29-2)
- (R)-2-Methylpiperazine bis((2S,3S)-2,3-dihydroxysuccinate) hydrate (CAS 1257867-52-9)
- pyrido[1,2-a]pyrimidin-4-one (CAS 23443-10-9)
- 3-Amino-2-hydroxy-3-phenylpropanoic acid (CAS 6049-55-4)
- Semaglutide Impurity 123 (CAS 71997-93-8)
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