Miconazole EP Impurity G CAS 909277-72-1
| CAS No. | 909277-72-1 |
| Molecular Formula | C18H14Cl4N2O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Miconazole EP Impurity G meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Miconazole EP Impurity G (CAS 909277-72-1) is a certified pharmaceutical impurity reference standard with the molecular formula C18H14Cl4N2OHNO3 and a molecular weight of 479.13 g/mol.
Based on its molecular formula C18H14Cl4N2OHNO3, Miconazole EP Impurity G contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 479.13 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C18H14Cl4N2O HNO3 |
| Molecular Weight | 479.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Miconazole Standards
- Miconazole-d5 Nitrate (CAS 1216653-51-8)
- Miconazole EP Impurity H (CAS 181931-30-6)
- Miconazole EP Impurity H (CAS 181931-30-6（free base）)
- Miconazole Impurity H nitarte salt (CAS 203264-09-9)
- Miconazole Nitrate (CAS 228321-87-7)
- Miconazole (CAS 22916-47-8)
- Miconazole EP Impurity D (CAS 24168-96-5)
- Miconazole EP Impurity I (CAS 24169-00-4)
Recommended Standards
- Ezetimibe Impurity 85 (CAS CATO-C4X-109885)
- Dasatinib Impurity 77 (CAS CATO-C4X-160777)
- Vancomycin EP Impurity I (CAS CATO-C4X-177510)
- 2-(7-Methyl-3-oxoisobenzofuran-1(3H)-ylidene)acetonitrile (CAS 58138-77-5)
- 5-Cyclobutylpyrimidine-2,4(1H,3H)-dione (CAS 63676-30-2)
- 2-Bromo-4-fluoro-6-iodophenol (CAS 1335094-10-4)
- 6-Bromo-1h-pyrazolo[3,4-b]pyridine-3-carboxylicacid (CAS 1782248-22-9)
- 4-Cyclopropoxy-6-methoxynicotinonitrile (CAS 1243354-92-8)
- 3-(Trifluoromethylthio) isonicotinonitrile (CAS 1204235-20-0)
- Semaglutide Impurity 186 (CAS CATO-C4X-2226186)
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