6-Amino-1-(3-chloro-2-methylphenyl)pyrimidine-2,4(1H,3H)-dione CAS 910443-01-5
| CAS No. | 910443-01-5 |
| Molecular Formula | C11H10ClN3O2 |
| Molecular Weight | 251.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 251.67 g/mol gives 6-Amino-1-(3-chloro-2-methylphenyl)pyrimidine-2,4(1H,3H)-dione distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
6-Amino-1-(3-chloro-2-methylphenyl)pyrimidine-2,4(1H,3H)-dione (CAS 910443-01-5) is a high-purity analytical reference standard with the molecular formula C11H10ClN3O2 and a molecular weight of 251.67 g/mol.
The molecular framework of 6-Amino-1-(3-chloro-2-methylphenyl)pyrimidine-2,4(1H,3H)-dione (C11H10ClN3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Amino-1-(3-chloro-2-methylphenyl)pyrimidine-2,4(1H,3H)-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H10ClN3O2 |
| Molecular Weight | 251.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- Methyl 5-amino-1-(3-chlorophenyl)-1H-pyrazole-4-carboxylate (CAS 121716-20-9)
- Methyl 5-amino-1-(4-chlorophenyl)-1H-pyrazole-4-carboxylate (CAS 121716-21-0)
- Methyl 5-amino-1-(2-chlorophenyl)-1H-pyrazole-4-carboxylate (CAS 1264044-28-1)
- 5-Amino-1-(4-chlorobenzyl)-1h-1,2,3-triazole-4-carboxamide (CAS 132269-38-6)
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Recommended Standards
- 6-Amino-1-(2-chlorobenzyl)pyrimidine-2,4(1H,3H)-dione (CAS 638136-51-3)
- 6-Amino-1-(4-chlorophenyl)-3-methylpyrimidine-2,4(1H,3H)-dione (CAS 7629-18-7)
- 6-((4-Chlorophenyl)amino)-3-methylpyrimidine-2,4(1H,3H)-dione (CAS 58137-45-4)
- 6-Amino-1-benzyl-5-chloropyrimidine-2,4(1H,3H)-dione (CAS 343347-98-8)
- 3-(Benzylthio)-5-(2,2-dimethoxyethyl)-4-methyl-4H-1,2,4-triazole (CAS 240799-77-3)
- 4-Fluoro-2-((2-methylpiperidin-1-yl)methyl)benzenethiol (CAS 1443303-64-7)
- 5-Bromo-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS 1256358-92-5)
- N-[(4-Chlorophenyl)sulfonyl]-N-(3-methylphenyl)glycine (CAS 445227-98-5)
- 5-Bromo-1H-benzo[d]imidazole-2-carboxylic acid (CAS 40197-20-4)
- 4-(But-3-yn-1-yl)-2,2-dimethylmorpholine (CAS 1341194-07-7)
- Methyl 6-amino-2-fluoro-3-methylbenzoate (CAS 851045-19-7)
- Methyl 5-((methylsulfonyl)methyl)furan-2-carboxylate (CAS 1092287-20-1)
- 2-(N,N-dimethylamine)-3-cyanopyridine (CAS 60138-76-3)
- D-allo-Thr5-Semaglutide (CAS CATO-C4X-2226243)
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