(αS)-2-Chloro-4-fluoro-α-methyl-benzenemethanol CAS 911218-03-6
| CAS No. | 911218-03-6 |
| Molecular Formula | C8H8ClFO |
| Molecular Weight | 174.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(αS)-2-Chloro-4-fluoro-α-methyl-benzenemethanol (CAS 911218-03-6) is a high-purity analytical reference standard with the molecular formula C8H8ClFO and a molecular weight of 174.60 g/mol.
Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, (αS)-2-Chloro-4-fluoro-α-methyl-benzenemethanol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 174.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (αS)-2-Chloro-4-fluoro-α-methyl-benzenemethanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8ClFO |
| Molecular Weight | 174.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
Related S Standards
- 1-(3-Chloro-5-fluorobenzyl)hydrazine (CAS 1000805-95-7)
- (3-Chloro-2-fluorobenzyl)hydrazine (CAS 1000805-97-9)
- (R)-1-(4-Chloro-3-fluorophenyl)ethan-1-ol (CAS 1016646-05-1)
- (R)-1-(4-Chloro-2-fluorophenyl)ethan-1-ol (CAS 1016646-16-4)
- 5-Chloro-2-(N,N-dimethylamino)-3-fluoropyridine (CAS 1020253-19-3)
- 3-chloro-2-hydroxypropanesulphonicacid (CAS 107-57-3)
- 1-(2-Chloro-4-fluorophenyl)ethanol (CAS 112108-68-6)
- 1-Chloro-4-fluoro-2-methoxy-3-methylbenzene (CAS 1208076-24-7)
Recommended Standards
- (S)-1-(3-Chloro-4-fluorophenyl)ethan-1-ol (CAS 911218-02-5)
- [(2-Chloro-4-fluorophenyl)methyl]hydrazine (CAS 51860-05-0)
- (6-Chloro-2-fluoro-3-methylphenyl)methanol (CAS 261762-84-9)
- [2-(Chloromethyl)-5-Fluorophenyl]Methanol (CAS 313232-91-6)
- N,N-Dimethyl-4-(1,3,4-oxadiazol-2-yl)aniline (CAS 90839-97-7)
- 2,2-Dimethoxy-3-Fluoro-1-Propanol (CAS 62741-32-6)
- Cinchonine hydrochloride (CAS 5949-11-1)
- (S)-6,7-Dihydro-5H-pyrrolo[1,2-a]imidazol-6-ol (CAS 1219019-23-4)
- 2-((tert-Butoxycarbonyl)amino)-6-methylthieno[2,3-b]pyridine-3-carboxylic acid (CAS 953821-10-8)
- 1-Chloro-3-(3,4,5-trimethoxyphenyl)propan-2-one (CAS 100389-03-5)
- 4-Cyclopropoxy-6-(trifluoromethyl)picolinonitrile (CAS 1243360-50-0)
- 3-Amino-2-(methylamino)phenol (CAS 163808-12-6)
- Tributylphosphate (CAS 126-73-8)
- Liraglutide Impurity 15 TFA Salt (CAS CATO-C4X-199215)
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