6-Hydroxy-4-methyl-2-oxo-2H-chromene-5-carbaldehyde CAS 91136-60-6

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Hydroxy-4-methyl-2-oxo-2H-chromene-5-carbaldehyde.

6-Hydroxy-4-methyl-2-oxo-2H-chromene-5-carbaldehyde (CAS 91136-60-6) is a high-purity analytical reference standard with the molecular formula C11H8O4 and a molecular weight of 204.18 g/mol.

6-Hydroxy-4-methyl-2-oxo-2H-chromene-5-carbaldehyde (C11H8O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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