tert-Butyl 3,3-difluoropiperidine-1-carboxylate CAS 911634-75-8
| CAS No. | 911634-75-8 |
| Molecular Formula | C10H17F2NO2 |
| Molecular Weight | 221.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
tert-Butyl 3,3-difluoropiperidine-1-carboxylate (CAS 911634-75-8), molecular formula C10H17F2NO2 and molecular weight 221.24 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of tert-Butyl 3,3-difluoropiperidine-1-carboxylate (C10H17F2NO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), tert-Butyl 3,3-difluoropiperidine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H17F2NO2 |
| Molecular Weight | 221.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- tert-Butyl (3S)-3-(difluoromethyl)pyrrolidine-1-carboxylate (CAS 2307279-81-6)
- Ilaprazole Impurity 211 (CAS CATO-C4X-1130211)
- Tert-butyl (3,3-difluorocyclobutyl)(methyl)carbamate (CAS 2299776-40-0)
- 4-Pentanamidobenzoic acid (CAS 100390-76-9)
- 2-Chloro-6-(2-(dimethylamino)ethoxy)pyridin-4-amine (CAS 1186112-12-8)
- N-benzyl-3-(trifluoromethyl)piperidin-3-amine dihydrochloride (CAS 2306261-88-9)
- 6-Chloro-5-(difluoromethyl)-3-hydroxypyridine-2-sulfonamide (CAS 1807060-34-9)
- N-(4-Bromo-2-fluorobenzyl)propan-1-amine (CAS 1094257-47-2)
- 6-Isopropoxyhexane-1-sulfonyl chloride (CAS 1340133-14-3)
- 2-(Biphenyl-2-yloxy)-propionic acid (CAS 119411-78-8)
- 3-((2,5-Dichlorobenzyl)oxy)piperidine hydrochloride (CAS 1289386-64-6)
- Phosphoramidothioic Dichloride (CAS 14475-36-6)
- Isopropyl 4-oxopentanoate (CAS 21884-26-4)
- Semaglutide-d8 Tetratrifluoroacetate (CAS CATO-C4X-222617)
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