3-(4-Chlorophenyl)-5-methylisoxazole-4-carboxylic acid CAS 91182-87-5
| CAS No. | 91182-87-5 |
| Molecular Formula | C11H8ClNO3 |
| Molecular Weight | 237.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(4-Chlorophenyl)-5-methylisoxazole-4-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 3-(4-Chlorophenyl)-5-methylisoxazole-4-carboxylic acid (CAS 91182-87-5), a certified reference material (molecular formula C11H8ClNO3, MW 237.64 g/mol) for analytical method development and quality control.
Based on its molecular formula C11H8ClNO3, 3-(4-Chlorophenyl)-5-methylisoxazole-4-carboxylic acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 237.64 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(4-Chlorophenyl)-5-methylisoxazole-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8ClNO3 |
| Molecular Weight | 237.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorophenyl Standards
- 1-(2-chlorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxylic acid (CAS 103058-59-9)
- 1-(4-chlorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxylic acid (CAS 103058-60-2)
- 1-(3-Chlorophenyl)-5-methyl-1h-1,2,4-triazole-3-carboxylic acid (CAS 1060795-68-7)
- Methyl 5-(3-chlorophenyl)isoxazole-4-carboxylate (CAS 1065074-27-2)
- Methyl 4-(4-chlorophenyl)isoxazole-5-carboxylate (CAS 1072944-87-6)
- 2-(5-(4-Chlorophenyl)-4H-1,2,4-triazol-3-yl)acetic acid (CAS 1203243-07-5)
- 5-(2-Chlorophenyl)-1-methyl-1H-1,2,3-triazole-4-carboxylic acid (CAS 1267386-96-8)
- Methyl 2-(3-chlorophenyl)oxazole-4-carboxylate (CAS 154405-97-7)
Recommended Standards
- 3-(3-Chlorophenyl)-5-methyl-1,2-oxazole-4-carboxylic acid (CAS 92545-95-4)
- 3-(4-Methoxyphenyl)isoxazole-5-carbonyl chloride (CAS 890095-73-5)
- 2-Chloro-N-(5-phenyl-[1,3,4]oxadiazol-2-yl)-acetamide (CAS 7659-20-3)
- 3-(Benzo[d][1,3]dioxol-5-yl)-5-(chloromethyl)isoxazole (CAS 890094-21-0)
- (3,4-Dichlorophenyl)(furan-3-yl)methanol (CAS 1249678-85-0)
- Tert-butyl (2,2,3,3-tetrafluoropropyl) carbonate (CAS 1980035-09-3)
- 1-[(2-aminophenyl)methyl]pyrrolidine-2,5-dione (CAS 500896-60-6)
- 6,7,8-Trimethoxyquinazolin-4(3H)-one (CAS 16064-19-0)
- α-[2,4-Bis(1H-1,2,4-triazol-1-yl)phenyl]-α-(1H-1,2,4-triazol-1-ylmethyl)-1H-1,2,4-triazole-1-ethanol (CAS 871550-18-4)
- (2'-Formyl[1,1'-biphenyl]-4-yl)acetonitrile (CAS 893737-87-6)
- Ethyl 4-(diethylamino)-8-isopropylquinoline-3-carboxylate (CAS 1279213-98-7)
- Empagliflozin impurity 250 (CAS CATO-C4X-1065250)
- 2-Acetamidopyridine-4-boronic Acid Pinacol Ester (CAS 1220220-21-2)
- Peptide 434 (CAS CATO-CPTD788434)
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