N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine CAS 912569-84-7

Purity >90%In StockPharmaceutical Standards
CAS No.912569-84-7
Molecular FormulaC36H50ClN3O10S
Molecular Weight752.31 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine CAS 912569-84-7 chemical structure

Description

The occurrence of N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine (CAS 912569-84-7), a certified reference material (molecular formula C36H50ClN3O10S, MW 752.31 g/mol) for analytical method development and quality control.

N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine (C36H50ClN3O10S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC36H50ClN3O10S
Molecular Weight752.31 g/mol
Purity>90%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentCl-containing
Nitrogen Atoms3
Sulfur Atoms1

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