Cenobamate impurity 8 CAS 913087-59-9
| CAS No. | 913087-59-9 |
| Molecular Formula | C10H10ClN5O2 |
| Molecular Weight | 267.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C10H10ClN5O2, Cenobamate impurity 8 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 267.67 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Cenobamate impurity 8 (CAS 913087-59-9) is a certified pharmaceutical impurity reference standard with the molecular formula C10H10ClN5O2 and a molecular weight of 267.67 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H10ClN5O2 |
| Molecular Weight | 267.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Cenobamate Standards
- Cenobamate impurity 01 (CAS 913089-08-4)
- Cenobamate S isomer (CAS CATO-C4X-24161)
- Cenobamate impurity 12 (CAS 913088-45-6)
- Cenobamate Impurity 31 (CAS 913088-83-2)
- Cenobamate Impurity 32 (CAS CATO-C4X-241632)
- Cenobamate Impurity 36 (CAS 913089-09-5)
- Cenobamate Impurity 57 (CAS 913087-62-4)
- Cenobamate Impurity 58 (CAS 913087-66-8)
Recommended Standards
- Cenobamate (CAS 913088-80-9)
- Tivozanib Impurity 9 (CAS 1808274-21-6)
- Cenobamate impurity 6 (CAS 913088-81-0)
- 3-(4-Chloro-5-cyclopropyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)propan-1-amine (CAS 1006454-49-4)
- Cenobamate impurity 3 (CAS 1259059-77-2)
- Irinotecan Impurity 50 (CAS CATO-C4X-166750)
- Cefathiamidine Impurity 18 (CAS CATO-C4X-133718)
- Esmolol Impurity 69 (CAS CATO-C4X-189169)
- 2-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine 1-oxide (CAS 911405-87-3)
- 2-Azaspiro[4.5]Decan-8-one hydrochloride (CAS 2007910-03-2)
- N-(3-Methoxybenzyl)-3,4-dihydro-2H-pyrrol-5-amine (CAS 753466-10-3)
- 6-BROMO-4-FLUOROBENZO[D]THIAZOLE (CAS 1610021-37-8)
- 3-(Piperidin-1-yl)-N-(pyridin-3-ylmethyl)propan-1-amine (CAS 1042553-62-7)
- Galanin-Like Peptide (rat) trifluoroacetate salt (CAS 245114-97-0)
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