4-(5-Bromopyridin-3-yl)-6-methylpyrimidin-2-amine CAS 913322-65-3
| CAS No. | 913322-65-3 |
| Molecular Formula | C10H9BrN4 |
| Molecular Weight | 265.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(5-Bromopyridin-3-yl)-6-methylpyrimidin-2-amine (CAS 913322-65-3), molecular formula C10H9BrN4 and molecular weight 265.11 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(5-Bromopyridin-3-yl)-6-methylpyrimidin-2-amine (C10H9BrN4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H9BrN4 |
| Molecular Weight | 265.11 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
Related Bromopyridin Standards
- 4-((3-Bromopyridin-2-yl)oxy)aniline (CAS 901925-53-9)
- N2-(6-Bromopyridin-2-yl)pyridine-2,6-diamine (CAS 427900-26-3)
- N-(5-Bromopyridin-3-yl)ethanesulfonamide (CAS 1086065-44-2)
- N-(5-bromopyridin-3-yl)-N-methylmethanesulfonamide (CAS 1240287-01-7)
- N-((5-Bromopyridin-3-yl)methyl)methanesulfonamide (CAS 173999-05-8)
- 1-(5-Bromopyridin-2-yl)-N-methylmethanesulfonamide (CAS 2167715-17-3)
- N-(5-bromopyridin-2-yl)ethanesulfonamide (CAS 89856-50-8)
- 1216804-34-0 6-[(5-Bromopyridin-3-yl)oxy]pyridin-3-amine KS-00003TRB (CAS 1216804-34-0)
Recommended Standards
- 4-(3-Bromo-2-oxopyrrolidin-1-yl)benzonitrile (CAS 213978-36-0)
- 4-Bromo-1-(pyridin-3-ylmethyl)pyridin-2(1h)-one (CAS 2090651-53-7)
- 4-Bromo-1-(pyridin-4-ylmethyl)pyridin-2(1h)-one (CAS 2090429-68-6)
- 3-Iodo-4-(methylthio)aniline (CAS 23153-02-8)
- Bis(4-fluorophenyl)phosphine oxide (CAS 94940-35-9)
- (2S)-2-[[[[(1R,2R)-2-(Dipropylamino)cyclohexyl]amino]thioxomethyl]amino]-N,3,3-trimethylbutanamide (CAS 860994-52-1)
- Gentamicin B1 • xAcetate Salt (CAS 36889-16-4（free base）)
- 3-(Oxetan-3-yl)piperidine (CAS 1273568-27-6)
- 1-Ethynyl-4-((4-((4-nitrophenyl)-ethynyl)phenyl)ethynyl)benzene (CAS 377776-32-4)
- n-(4-Isopropylphenyl)furan-2-carboxamide (CAS 306743-27-1)
- 3,6-Bis(5-bromothiophen-2-yl)-2,5-didodecylpyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione (CAS 1232880-65-7)
- 4-Methoxy-2-naphthaldehyde (CAS 123239-64-5)
- n-[(methylsulfanyl)(morpholin-4-yl)methylidene]aniline (CAS 21114-92-1)
- Peptide Impurity 06 (CAS CATO-CPTD788806)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com