4-(4-Fluoro-3-(trifluoromethyl)phenyl)thiazol-2-amine CAS 913686-08-5
| CAS No. | 913686-08-5 |
| Molecular Formula | C10H6F4N2S |
| Molecular Weight | 262.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-(4-Fluoro-3-(trifluoromethyl)phenyl)thiazol-2-amine (CAS 913686-08-5) is a high-purity analytical reference standard with the molecular formula C10H6F4N2S and a molecular weight of 262.23 g/mol.
The molecular framework of 4-(4-Fluoro-3-(trifluoromethyl)phenyl)thiazol-2-amine (C10H6F4N2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 4-(4-Fluoro-3-(trifluoromethyl)phenyl)thiazol-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H6F4N2S |
| Molecular Weight | 262.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Fluoro Standards
- 3-Fluoro-4-(2-methoxyphenoxy)benzoic acid (CAS 1021245-91-9)
- 4-(3-Fluoro-5-hydroxyphenyl)-2-methoxybenzoic acid (CAS 1261890-38-3)
- 4-(2-Fluoro-3-(trifluoromethyl)phenyl)thiazol-2(3h)-imine (CAS 444143-17-3)
- 4-(2-Fluoro-4-(trifluoromethyl)phenyl)thiazol-2-amine (CAS 886494-92-4)
- 4-(2-Fluoro-5-(trifluoromethyl)phenyl)thiazol-2-amine (CAS 199602-12-5)
- 4-(4-Fluoro-2-(trifluoromethyl)phenyl)thiazol-2-amine (CAS 886494-94-6)
- Ethyl 2-fluoro-4-(2-hydroxypyrimidin-5-yl)benzoate (CAS 1111104-20-1)
- 2-(8-Fluoro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)-2-oxoacetic acid (CAS 1144466-00-1)
Recommended Standards
- 4-Amino-4'-(trifluoromethyl)-[1,1'-biphenyl]-3-carbonitrile (CAS 405520-49-2)
- 4-(3-(Trifluoromethyl)phenyl)-1H-pyrrolo[2,3-b]pyridine (CAS 916173-13-2)
- 4-Amino-N-(2-(2,2,2-trifluoroethoxy)ethyl)benzamide (CAS 924710-26-9)
- 6-Amino-8-trifluoromethylphenanthridine (CAS 651055-83-3)
- 3-amino-1-(cyclobutylmethyl)thiourea (CAS 1095592-96-3)
- 2-(Benzylamino)-4-chlorobenzonitrile (CAS 296259-54-6)
- tert-Butyl N-(3-chloro-4-hydroxyphenyl)-N-ethylcarbamate (CAS 1881293-22-6)
- 3-(2H-1,3-Benzodioxol-5-yl)-3-(2,5-dimethyl-1H-pyrrol-1-yl)-N-(4-fluorophenyl)propanamide (CAS 866040-39-3)
- Perfluoro-C8-14-alkylalcohols (CAS 68391-08-2)
- 2-chloro-6-hydrazinyl-9H-purine (CAS 5404-88-6)
- (2,5-Dichlorophenyl)(phenyl)methanamine Hydrochloride (CAS 1461706-28-4)
- Benzyl (2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)ethyl)glycinate hydrochloride (CAS 511534-93-3)
- 1H-indole-4-carboxylic acid 2124-55-2 A15369 Indole-4-carboxylic acid (CAS 2124-55-2)
- Vialox Peptide(Pentapeptide-3) (CAS 135679-88-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com