4-(Difluoromethoxy)-3-hydroxybenzoic acid CAS 913985-07-6
| CAS No. | 913985-07-6 |
| Molecular Formula | C8H6F2O4 |
| Molecular Weight | 204.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C8H6F2O4, 4-(Difluoromethoxy)-3-hydroxybenzoic acid contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 204.13 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
4-(Difluoromethoxy)-3-hydroxybenzoic acid (CAS 913985-07-6), molecular formula C8H6F2O4 and molecular weight 204.13 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(Difluoromethoxy)-3-hydroxybenzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6F2O4 |
| Molecular Weight | 204.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Difluoromethoxy Standards
- 5-(Difluoromethoxy)-2-nitroaniline (CAS 1137860-96-8)
- 3-(Difluoromethoxy)-2-nitroaniline (CAS 1261605-09-7)
- 4-(Difluoromethoxy)-3-nitroaniline, >98% (CAS 1261747-80-1)
- 2-(Difluoromethoxy)-6-nitroaniline (CAS 170986-71-7)
- 2-(Difluoromethoxy)-6-hydroxybenzoic acid (CAS 1799439-06-7)
- 2-(difluoromethoxy)-5-nitroaniline (CAS 54939-58-1)
- 1-(4-(Difluoromethoxy)-3-fluorophenyl)ethan-1-one (CAS 1180015-83-1)
- 1-[4-(Difluoromethoxy)-2-fluorophenyl]ethan-1-one (CAS 1180016-06-1)
Recommended Standards
- Pantoprazole Impurity 61 (CAS 887412-09-1)
- Pantoprazole Impurity 28 (CAS 97963-76-3)
- 6,6-Difluoro-6,7-dihydro-5h-pyrazolo[5,1-b][1,3]oxazine-3-carboxylic acid (CAS 2091693-39-7)
- Pantoprazole Impurity 41 (CAS 22236-06-2)
- (S)-N,2-Dihydroxypropanimidamide (CAS 1609388-55-7)
- 2-(Difluoromethyl)-5-methoxy-6-methylpyridine-3-acetic acid (CAS 1807111-80-3)
- N-Cyclopropyl-3-fluoro-5-(1H-indazol-5-yl)-4-methylbenzamide (CAS 651780-48-2)
- Benzyloxycarbonylglycyl-L-leucyl-L-phenylalanine chloromethyl ketone (CAS 41658-44-0)
- 4-Chloro-N'-(furan-2-ylmethylene)benzohydrazide (CAS 93418-01-0)
- 2,7-dimethylimidazo[1,2-a]pyridine-3-carboxylic acid (CAS 81438-53-1)
- 5-(3-Bromobenzyl)-2-morpholinothiazol-4-amine (CAS 1387573-85-4)
- (S)-2-(1-Phenylethyl)isoindoline-1,3-dione (CAS 3976-26-9)
- Benzyl 5-methyl-3-oxo-2,3,6,7-tetrahydro-1H-azepine-1-carboxylate (CAS 1956383-20-2)
- Tetrapeptide-3 (CAS 827306-97-8)
Why CATO?
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