4-Bromo-1-(tert-butoxycarbonyl)-1H-indole-3-carboxylic acid CAS 914203-00-2
| CAS No. | 914203-00-2 |
| Molecular Formula | C14H14BrNO4 |
| Molecular Weight | 340.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Bromo-1-(tert-butoxycarbonyl)-1H-indole-3-carboxylic acid.
CATO supplies 4-Bromo-1-(tert-butoxycarbonyl)-1H-indole-3-carboxylic acid (CAS 914203-00-2), a certified reference material (molecular formula C14H14BrNO4, MW 340.17 g/mol) for analytical method development and quality control.
The molecular framework of 4-Bromo-1-(tert-butoxycarbonyl)-1H-indole-3-carboxylic acid (C14H14BrNO4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H14BrNO4 |
| Molecular Weight | 340.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
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Recommended Standards
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- 6-Bromo-3-methyl-3h-naphtho[1,2,3-de]quinoline-2,7-dione (CAS 81-85-6)
- (S)-2-(2-Amino-3-(5-bromo-1H-indol-3-yl)propanamido)acetic acid (CAS 918957-45-6)
- 2-Bromo-4-(tert-butyl)phenyl 3-pyrrolidinylmethyl-ether hydrochloride (CAS 1219948-97-6)
- 2-Aminopyridine-4-sulfonamide hydrochloride (CAS 2137792-99-3)
- 2-(2-(1-Methylene-3-oxoisoindolin-2-yl)acetamido)acetic acid (CAS 62100-35-0)
- 3-(4-Bromobenzoyl)-1h-indole (CAS 1097119-36-2)
- 1,5-Dimethyl-1H-1,2,4-triazole-3-carboxylic acid (CAS 1393540-58-3)
- 2-((2,8-Dimethylquinolin-4-yl)amino)benzoic acid (CAS 294667-95-1)
- 1-(3-Chloro-2-fluorophenyl)cyclopentanecarbonitrile (CAS 1260654-34-9)
- Amorofen lmpurity 28 (CAS CATO-C4X-154228)
- 1-(3-Bromo-4-fluorobenzyl)-N-methylpyrrolidine-2-carboxamide (CAS 1270676-77-1)
- Peptide 6A (H-6905.0005) (CAS 73549-32-3)
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