4-(1,1-Dioxido-3-oxoisothiazolidin-2-yl)-2-methylbenzenesulfonyl chloride CAS 914203-24-0
| CAS No. | 914203-24-0 |
| Molecular Formula | C10H10ClNO5S2 |
| Molecular Weight | 323.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 323.77 g/mol gives 4-(1,1-Dioxido-3-oxoisothiazolidin-2-yl)-2-methylbenzenesulfonyl chloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 4-(1,1-Dioxido-3-oxoisothiazolidin-2-yl)-2-methylbenzenesulfonyl chloride (CAS 914203-24-0), a certified reference material (molecular formula C10H10ClNO5S2, MW 323.77 g/mol) for analytical method development and quality control.
The molecular framework of 4-(1,1-Dioxido-3-oxoisothiazolidin-2-yl)-2-methylbenzenesulfonyl chloride (C10H10ClNO5S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(1,1-Dioxido-3-oxoisothiazolidin-2-yl)-2-methylbenzenesulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10ClNO5S2 |
| Molecular Weight | 323.77 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Dioxido Standards
- 5-(1,1-Dioxido-3-oxoisothiazolidin-2-yl)-2-methylbenzenesulfonyl chloride (CAS 927966-15-2)
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- N-(4-(1,1-Dioxido-1,2-thiazinan-2-yl)phenyl)-3,3-dimethylbutanamide (CAS 899979-46-5)
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- N-(1,1-Dioxido-2,3-dihydrothiophen-3-yl)-N-(4-ethoxyphenyl)-2-methoxyacetamide (CAS 863020-79-5)
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