4-(3,4-Dihydroisoquinolin-2(1H)-yl)-3-(trifluoromethyl)aniline CAS 914348-87-1
| CAS No. | 914348-87-1 |
| Molecular Formula | C16H15F3N2 |
| Molecular Weight | 292.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
4-(3,4-Dihydroisoquinolin-2(1H)-yl)-3-(trifluoromethyl)aniline (CAS 914348-87-1), molecular formula C16H15F3N2 and molecular weight 292.30 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-(3,4-Dihydroisoquinolin-2(1H)-yl)-3-(trifluoromethyl)aniline (C16H15F3N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 292.30 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H15F3N2 |
| Molecular Weight | 292.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Dihydroisoquinolin Standards
- 2-(3,4-Dihydroisoquinolin-2(1H)-yl)-5-(trifluoromethyl)aniline (CAS 175134-94-8)
- 4-((3,4-Dihydroisoquinolin-2(1H)-yl)sulfonyl)-5-methylisoxazol-3-amine (CAS 1354513-79-3)
- 2-(3,4-Dihydroisoquinolin-1-ylmethyl)isoindole-1,3-dione (CAS 88422-83-7)
- 4-(3,4-Dihydroisoquinolin-2(1H)-ylsulfonyl)aniline (CAS 7252-02-0)
- 2-(3,4-Dihydroisoquinolin-2(1H)-yl)-6-isopropylpyrimidine-4-carboxylic acid (CAS 1182002-05-6)
- 3-(3,4-Dihydroisoquinolin-2(1H)-ylcarbonyl)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid (CAS 500128-90-5)
- Ethyl 2-(3,4-dihydroisoquinolin-2(1H)-yl)-4-methylpyrimidine-5-carboxylate (CAS 903446-37-7)
- 3-((3,4-Dihydroisoquinolin-2(1H)-yl)sulfonyl)benzonitrile (CAS 923836-09-3)
Recommended Standards
- 3,5-Dimethyl-3-(3,4,5-trifluorophenyl)-propiophenone (CAS 898778-12-6)
- 4-ethyl-12-(trifluoromethyl)-2,3,7,13-tetrazatricyclo[7.4.0.0²⁶]trideca-1(13),3,5,9,11-pentaen-8-one (CAS 2649318-85-2)
- 3,4-Dimethyl-3-(3,4,5-trifluorophenyl)-propiophenone (CAS 898778-09-1)
- 4-Methyl-5-[3-(trifluoromethyl)benzenesulfinyl]-1,2,3-thiadiazole (CAS 338397-20-9)
- 1,4-Bis(chloromethyl)-2-((3,7-dimethyloctyl)oxy)-5-methoxybenzene (CAS 174097-32-6)
- 2-(4-Nitrophenyl)thiazole-4-carbaldehyde (CAS 3474-89-3)
- methyl 2-methyl-1-(propan-2-yl)-1H-pyrrole-3-carboxylate (CAS 224180-63-6)
- 1-(6-(2-Methoxyphenyl)pyridazin-3-yl)piperidin-4-amine (CAS 1338677-56-7)
- N1-(6-chloro-2-methylpyrimidin-4-yl)-N3,N3-diethylpropane-1,3-diamine (CAS 857011-25-7)
- 3,4-Dibromo-2-fluorobenzotrifluoride (CAS 1806294-91-6)
- 4-Amino-N-benzylbenzamide (CAS 54977-92-3)
- N-Boc-L-trans-4-ethoxyproline (CAS 146060-18-6)
- 5-Nitropyrimidine-2-carbonitrile (CAS 1352139-23-1)
- Tau Peptide (306-317) trifluoroacetate salt (CAS 1003007-59-7)
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