2-Bromo-6-methylpyrazine CAS 914452-71-4
| CAS No. | 914452-71-4 |
| Molecular Formula | C5H5BrN2 |
| Molecular Weight | 173.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 2-Bromo-6-methylpyrazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
2-Bromo-6-methylpyrazine (CAS 914452-71-4), molecular formula C5H5BrN2 and molecular weight 173.01 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Bromo-6-methylpyrazine (C5H5BrN2) is characterized by a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C5H5BrN2 |
| Molecular Weight | 173.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 4-Bromo-2-methylpyrimidine (CAS 1114560-76-7)
- 2-Bromo-3-methylpyrazine (CAS 120984-76-1)
- 4-Bromo-5-methylpyrimidine (CAS 1257851-33-4)
- 3-Bromo-5-methylpyridazine (CAS 1257854-82-2)
- 2-Bromo-4-methylpyrimidine (CAS 130645-48-6)
- 4-Bromo-5-methylpyridazine (CAS 1368375-27-2)
- 3-Bromo-4-methylpyridazine (CAS 1416373-61-9)
- 5-Bromo-4-methylpyrimidine (CAS 1439-09-4)
Recommended Standards
- 2-Bromo-5-methylpyrazine (CAS 98006-90-7)
- 2-bromopyridin-4-amine (CAS 7598-35-8)
- 1-Iodopropane-3,3,3-d3 (stabilized with copper) (CAS 25493-16-7)
- 3-Bromo-1-vinyl-1H-pyrazole (CAS 923036-00-4)
- 1-(Quinazolin-2-yl)guanidine (CAS 102331-12-4)
- 2-Amino-8,9-dihydro-5H-benzo[7]annulen-7(6H)-one (CAS 740842-51-7)
- (Z)-benzyl but-2-enoate (CAS 92758-75-3)
- methyl 6-(methylamino)nicotinate (CAS 329365-27-7)
- 2-Methyl-1-(4-methylbenzyl)-6-oxo-N-(3-(trifluoromethyl)phenyl)-1,4,5,6-tetrahydropyridine-3-carboxamide (CAS 338748-82-6)
- 4-Bromo-1-butyl-3-((3,3,3-trifluoropropoxy)methyl)-1H-pyrazole (CAS 1856075-25-6)
- 2-(2-Fluoro-4-(isopropylamino)phenyl)quinoline-6-carboxylic acid (CAS 921211-16-7)
- (6-Bromo-5-methylpyridin-2-yl)methanamine (CAS 1823361-78-9)
- 5-(Thiophen-2-yl)dihydrothiophen-3(2H)-one (CAS 108372-48-1)
- Peptide 439 (CAS CATO-CPTD788439)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com