Ethyl 6-chloro-2,3-difluoro-4-(trifluoromethyl)phenylacetate CAS 914635-82-8
| CAS No. | 914635-82-8 |
| Molecular Formula | C11H8ClF5O2 |
| Molecular Weight | 302.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 302.63 g/mol gives Ethyl 6-chloro-2,3-difluoro-4-(trifluoromethyl)phenylacetate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ethyl 6-chloro-2,3-difluoro-4-(trifluoromethyl)phenylacetate (CAS 914635-82-8) is a high-purity analytical reference standard with the molecular formula C11H8ClF5O2 and a molecular weight of 302.63 g/mol.
The molecular framework of Ethyl 6-chloro-2,3-difluoro-4-(trifluoromethyl)phenylacetate (C11H8ClF5O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Ethyl 6-chloro-2,3-difluoro-4-(trifluoromethyl)phenylacetate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H8ClF5O2 |
| Molecular Weight | 302.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
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Recommended Standards
- 4-(Bromomethyl)-2-(2-chlorophenyl)-5-methylthiazole (CAS 663909-28-2)
- N-[(4-BRomo-3-chlorophenyl)methyl]cyclohexanamine (CAS 1509883-71-9)
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- 4-Bromomethyl-2-(4-chlorophenyl)-5-methylthiazole (CAS 113264-72-5)
- Z-Lys-OMe ยท HCl (CAS 26348-68-5)
- (6-Methoxypyrimidin-4-yl)methanamine hydrochloride (CAS 2306275-46-5)
- 4-Chloro-N-(quinolin-8-yl)benzenesulfonamide (CAS 33757-64-1)
- 4-Bromo-3-(2,6-difluoro-4-(trifluoromethyl)phenoxy)aniline (CAS 2244085-49-0)
- 3-Penten-1-yne (CAS 2206-23-7)
- 5-((Methylamino)methyl)isoxazole-3-carboxylic acid (CAS 893749-64-9)
- Ligustrazine Phosphate (CAS 1124-11-4)
- Methyl 2-fluoro-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (CAS 1629913-80-9)
- [2-(dimethylamino)ethyl](2-methylpropyl)amine (CAS 926205-56-3)
- Semaglutide impurity 64 (CAS CATO-C4X-222664)
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