2-Bromo-4,4,4-trifluoro-3-methylbutanoic acid CAS 914635-99-7
| CAS No. | 914635-99-7 |
| Molecular Formula | C5H6BrF3O2 |
| Molecular Weight | 235.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Bromo-4,4,4-trifluoro-3-methylbutanoic acid (C5H6BrF3O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-Bromo-4,4,4-trifluoro-3-methylbutanoic acid (CAS 914635-99-7), molecular formula C5H6BrF3O2 and molecular weight 235.00 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Bromo-4,4,4-trifluoro-3-methylbutanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H6BrF3O2 |
| Molecular Weight | 235.00 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- ethyl 2-bromo-3,3,3-trifluoropropanoate (CAS 108221-68-7)
- 2-Bromo-5,5,5-trifluoropentanoic acid (CAS 1346521-32-1)
- Methyl 2-bromo-4,4,4-trifluorobutanoate (CAS 1365988-14-2)
- 2-Bromo-3,3,3-trifluoropropyl acetate (CAS 383-68-6)
- 2-Bromo-4-fluoro-6-nitroaniline (CAS 10472-88-5)
- 3-Bromo-6-fluoro-2-nitroaniline (CAS 1119454-21-5)
- 4-Bromo-5-nitro-1h-pyrrole-2-carboxylic acid (CAS 1146289-91-9)
- 5-Bromo-3-fluoro-2-nitroaniline (CAS 1193385-18-0)
Recommended Standards
- 6-Methyl-2-(pyrazin-2-yl)-1,3,6,2-dioxazaborocane-4,8-dione (CAS 2221988-73-2)
- 3-Amino-6-bromo-5-fluoropicolinic acid (CAS 1052714-14-3)
- (T-4)-[N-[(Carboxy-κO)methyl]-N-methylglycinato(2-)-κN,κO]-2-pyrimidinylboron (CAS 1104637-59-3)
- 2-Bromoethylsulphur pentafluoride (CAS 109050-54-6)
- (Z)-4-Methylpent-2-ene-1,4-diol (CAS 50407-79-9)
- (3-(Hydroxymethyl)pyrrolidin-1-yl)(4-methyl-1,2,3-thiadiazol-5-yl)methanone (CAS 1247111-05-2)
- 2-Chloropyrimidine-5-carbonyl chloride (CAS 110099-99-5)
- LMP-420 (CAS 473870-63-2)
- Chlorempenthrin (CAS 54407-47-5)
- 7-Ethynyl-1-methyl-1H-indole (CAS 1075192-79-8)
- 5-Amino-4,6-diisopropylpyrimidine-2-carbonitrile (CAS 2397624-06-3)
- 2-(Chloromethyl)-3-(difluoromethyl)-4-(trifluoromethoxy)pyridine-5-carboxaldehyde (CAS 1804909-06-5)
- 2,3,6-Tribromo-4-methylphenol (CAS 36776-51-9)
- Insulin Degludec Impurity 18 (CAS CATO-C4X-215718)
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