2-(5-Bromothiophen-2-yl)-4-chloro-5-ethyl-6-methylpyrimidine CAS 915084-50-3

Purity 97%+In StockPharmaceutical Standards
CAS No.915084-50-3
Molecular FormulaC11H10BrClN2S
Molecular Weight317.63 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(5-Bromothiophen-2-yl)-4-chloro-5-ethyl-6-methylpyrimidine CAS 915084-50-3 chemical structure

Description

The molecular framework of 2-(5-Bromothiophen-2-yl)-4-chloro-5-ethyl-6-methylpyrimidine (C11H10BrClN2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

2-(5-Bromothiophen-2-yl)-4-chloro-5-ethyl-6-methylpyrimidine (CAS 915084-50-3), molecular formula C11H10BrClN2S and molecular weight 317.63 g/mol, is a CATO reference standard with documented purity and traceability.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-(5-Bromothiophen-2-yl)-4-chloro-5-ethyl-6-methylpyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC11H10BrClN2S
Molecular Weight317.63 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentCl/Br-containing
Nitrogen Atoms2
Sulfur Atoms1

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