4-Chloro-3-(2,2,2-trifluoroacetamido)benzoic acid CAS 915094-35-8
| CAS No. | 915094-35-8 |
| Molecular Formula | C9H5ClF3NO3 |
| Molecular Weight | 267.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-3-(2,2,2-trifluoroacetamido)benzoic acid.
CATO supplies 4-Chloro-3-(2,2,2-trifluoroacetamido)benzoic acid (CAS 915094-35-8), a certified reference material (molecular formula C9H5ClF3NO3, MW 267.59 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 4-Chloro-3-(2,2,2-trifluoroacetamido)benzoic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 267.59 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Chloro-3-(2,2,2-trifluoroacetamido)benzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H5ClF3NO3 |
| Molecular Weight | 267.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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- 7-Chloro-8-fluoro-2-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4(3H)-one (CAS 2454491-22-4)
- N-(2-Chloro-5-cyano-3-fluoropyridin-4-yl)-2,2,2-trifluoroacetamide (CAS 2454491-21-3)
- 2-Chloro-5-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS 1269233-15-9)
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Recommended Standards
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- N-((4-(5-Methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)butyramide (Palbociclib Impurity) (CAS 198470-91-6)
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