Ethyl 2,2-difluoro-2-(3-methoxyphenyl)acetate CAS 915133-57-2
| CAS No. | 915133-57-2 |
| Molecular Formula | C11H12F2O3 |
| Molecular Weight | 230.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 230.21 g/mol gives Ethyl 2,2-difluoro-2-(3-methoxyphenyl)acetate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ethyl 2,2-difluoro-2-(3-methoxyphenyl)acetate (CAS 915133-57-2), molecular formula C11H12F2O3 and molecular weight 230.21 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, Ethyl 2,2-difluoro-2-(3-methoxyphenyl)acetate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 230.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 2,2-difluoro-2-(3-methoxyphenyl)acetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H12F2O3 |
| Molecular Weight | 230.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Ethyl Standards
- 2,2-Difluoro-2-(4-methoxy-3,5-dimethylphenyl)acetic acid (CAS 1027514-02-8)
- Ethyl 2,2-Difluoro-2-(4-methoxyphenyl)acetate (CAS 112545-98-9)
- Ethyl 2,2-Difluoro-2-(2-methoxyphenyl)acetate (CAS 1150164-80-9)
- 4-(2,6-Difluoro-4-methoxyphenyl)butanoic acid (CAS 1184389-98-7)
- 2,2-Difluoro-2-(4-isopropoxyphenyl)acetic acid (CAS 1339100-72-9)
- 3,5-Difluoro-4-isobutoxybenzoic acid (CAS 1343670-92-7)
- 2,6-Difluoro-4-isopropoxybenzoic acid methyl ester (CAS 1394944-82-1)
- Methyl 4,5-difluoro-2-isopropoxybenzoate (CAS 1394955-02-2)
Recommended Standards
- Ethyl 1-cyclopropyl-3-(difluoromethyl)-1H-pyrazole-5-carboxylate (CAS 2540503-48-6)
- Ethyl 2,2-difluoro-3-hydroxy-3-phenylpropanoate (CAS 92207-60-8)
- Ethane-1,2-diyl bis(3-oxobutanoate) (CAS 5459-04-1)
- Ethyl 2,3-difluoro-5-methoxy-4-methylbenzoate (CAS 2586125-76-8)
- (5-Bromo-2-methylphenyl)(pyrrolidin-1-yl)methanone (CAS 1480283-73-5)
- 4-(2-Morpholinoethoxy)phenylboronic Acid (CAS 279262-19-0)
- Ethyl 6-isopropylnicotinate (CAS 118419-91-3)
- Benzyl (2-((2-hydroxyethyl)(methyl)amino)cyclohexyl)carbamate (CAS 1353960-81-2)
- 6-Hydroxy-5-(4-(pyrrolidin-1-ylsulfonyl)phenyl)nicotinic acid (CAS 1261978-04-4)
- 1-(2-Methylcyclopentyl)ethan-1-ol (CAS 101567-65-1)
- 2-Chloro-5-fluoroquinazolin-4-ol (CAS 769158-32-9)
- 6-Bromo-5-phenyl-1,2,4-triazin-3-amine (CAS 1321517-51-4)
- Loxoprofen Impurity 4 (CAS CATO-C4X-14884)
- (Leu31,Pro34)-Peptide YY (human) trifluoroacetate salt (CAS 179986-95-9)
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