4-chloro-8-fluoro-6-nitroquinoline-3-carbonitrile CAS 915369-86-7
| CAS No. | 915369-86-7 |
| Molecular Formula | C10H3ClFN3O2 |
| Molecular Weight | 251.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-chloro-8-fluoro-6-nitroquinoline-3-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 4-chloro-8-fluoro-6-nitroquinoline-3-carbonitrile (CAS 915369-86-7), a certified reference material (molecular formula C10H3ClFN3O2, MW 251.60 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 4-chloro-8-fluoro-6-nitroquinoline-3-carbonitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 251.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H3ClFN3O2 |
| Molecular Weight | 251.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
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- 3-hydroxy-N,N-dimethyl-2-phenylpropanamide (CAS 96392-51-7)
- 5-Bromo-2-(methylsulfonyl)-4-pyrimidinecarboxylic Acid (CAS 30321-94-9)
- 1-(3,4-Dichlorobenzyl)-1H-imidazole-4-carboxylic acid (CAS 1369066-17-0)
- 3,4-Dibromo-5-hydroxyfuran-2(5H)-one (CAS 766-38-1)
- 1-((1-(4-Ethoxyphenyl)-1h-tetrazol-5-yl)methyl)piperazine dihydrochloride (CAS 1351646-86-0)
- trans-1-Aminocyclopentane-1,3-dicarboxylic acid (CAS 67684-64-4)
- [Tyr0] Fibrinopeptide A, human (CAS 103226-11-5)
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