Methyl N-(3,4-difluorophenyl)-N-(methylsulfonyl)glycinate CAS 915902-40-8
| CAS No. | 915902-40-8 |
| Molecular Formula | C10H11F2NO4S |
| Molecular Weight | 279.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Methyl N-(3,4-difluorophenyl)-N-(methylsulfonyl)glycinate (CAS 915902-40-8), molecular formula C10H11F2NO4S and molecular weight 279.26 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Methyl N-(3,4-difluorophenyl)-N-(methylsulfonyl)glycinate (C10H11F2NO4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11F2NO4S |
| Molecular Weight | 279.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Recommended Standards
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- 2-Amino-N-cyclopropyl-6-(1,1-dimethylpropyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide (CAS 590352-39-9)
- Methyl 3-(cyclopropylmethoxy)-1-methyl-1H-pyrazole-5-carboxylate (CAS 2113855-11-9)
- 3-(4-Bromophenyl)prop-2-ynoic acid (CAS 25294-65-9)
- 2-[(2-Oxo-2-phenylethyl)sulfanyl]-4-(trifluoromethyl)pyrimidine-5-carbonitrile (CAS 303152-00-3)
- 1-[(3-chlorophenyl)methyl]-1h-pyrazole-4-carboxylic acid (CAS 1006494-84-3)
- 2-Fluoro-4-(pyrimidin-5-yl)benzaldehyde (CAS 893637-79-1)
- Semaglutide Impurity 157 (x TFA Salt) (CAS CATO-C4X-2226157)
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