(S)-2-amino-N-(2,2,2-trifluoroethyl)propanamide hydrochloride CAS 916176-69-7

Description

(S)-2-amino-N-(2,2,2-trifluoroethyl)propanamide hydrochloride (CAS 916176-69-7) is a high-purity analytical reference standard with the molecular formula C5H9F3N2OHCl and a molecular weight of 206.59 g/mol.

The molecular framework of (S)-2-amino-N-(2,2,2-trifluoroethyl)propanamide hydrochloride (C5H9F3N2OHCl) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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