4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-1-(3,5-difluorobenzyl)piperidine-4-carboxylic acid CAS 916422-01-0
| CAS No. | 916422-01-0 |
| Molecular Formula | C28H26F2N2O4 |
| Molecular Weight | 492.51 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-1-(3,5-difluorobenzyl)piperidine-4-carboxylic acid is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-1-(3,5-difluorobenzyl)piperidine-4-carboxylic acid (CAS 916422-01-0) is a high-purity analytical reference standard with the molecular formula C28H26F2N2O4 and a molecular weight of 492.51 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-1-(3,5-difluorobenzyl)piperidine-4-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 492.51 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-1-(3,5-difluorobenzyl)piperidine-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C28H26F2N2O4 |
| Molecular Weight | 492.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related H Standards
- 4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-1-(2,4-difluorobenzyl)piperidine-4-carboxylic acid (CAS 916422-05-4)
- 4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-1-(2,5-difluorobenzyl)piperidine-4-carboxylic acid (CAS 916422-03-2)
- 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(3',4'-dimethyl-[1,1'-biphenyl]-4-yl)propanoic acid (CAS 1379865-25-4)
- 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(3',4'-dimethyl-[1,1'-biphenyl]-3-yl)propanoic acid (CAS 1379884-40-8)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-benzoylphenyl)propanoic acid (CAS 117666-98-5)
- 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-(tert-butoxycarbonyl)piperidin-3-yl)propanoic acid (CAS 457060-97-8)
- 3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-(tert-butoxycarbonyl)piperidin-3-yl)propanoic acid (CAS 372144-11-1)
- (4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)benzoyl)-L-glutamic acid (CAS 1562435-65-7)
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