Ethyl 2-(2-(methylamino)pyrimidin-4-yl)-1H-indole-5-carboxylate CAS 916486-06-1
| CAS No. | 916486-06-1 |
| Molecular Formula | C16H16N4O2 |
| Molecular Weight | 296.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Ethyl 2-(2-(methylamino)pyrimidin-4-yl)-1H-indole-5-carboxylate (CAS 916486-06-1), a certified reference material (molecular formula C16H16N4O2, MW 296.32 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Ethyl 2-(2-(methylamino)pyrimidin-4-yl)-1H-indole-5-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 296.32 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H16N4O2 |
| Molecular Weight | 296.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 4 |
Related Ethyl Standards
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Recommended Standards
- Ethyl 2-([1,2,4]triazolo[1,5-a]pyrimidin-7-yl)-3-phenylpropanoate (CAS 477868-50-1)
- Ethyl 2-(3-oxo-1-phenyl-1,3-dihydroisobenzofuran-1-yl)acetate (CAS 6158-57-2)
- Ethyl 2-((2-phenyl-1H-benzo[d]imidazol-1-yl)oxy)acetate (CAS 339104-28-8)
- Ethyl 2-(9-benzyl-9H-purin-6-yl)acetate (CAS 948037-38-5)
- 2-(3-(Tert-butyl)-1-methyl-1h-pyrazol-4-yl)-2-oxoacetic acid (CAS 1489833-52-4)
- 5-Bromo-2′-chloro-2-hydroxybenzophenone (CAS 332104-54-8)
- (4-Chlorophenyl)(4-hydroxy-4-((p-tolylthio)methyl)piperidin-1-yl)methanone (CAS 478248-07-6)
- 1-(3-(3-(3-Fluorophenyl)-1,2,4-oxadiazol-5-yl)pyridin-2-yl)piperidine-4-carboxylic acid (CAS 1232799-10-8)
- 3-((4-Methylpiperidin-1-yl)methyl)benzaldehyde (CAS 1443323-34-9)
- Ethyl 2-(3-bromo-6-cyano-2-methoxyphenyl)acetate (CAS 1805188-43-5)
- Methyl 5-(aminomethyl)bicyclo[3.2.1]Octane-1-carboxylate (CAS 2167650-44-2)
- 5-((2-Chloro-5-methylphenoxy)methyl)furan-2-carbohydrazide (CAS 832737-50-5)
- Abacavir Impurity 2 (CAS 168960-19-8)
- Semaglutide Impurity 146 (CAS 2645421-68-5)
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