5-(4-(4-Chloro-3-(trifluoromethyl)phenyl)piperazin-1-yl)pyrrolidin-2-one CAS 91703-25-2
| CAS No. | 91703-25-2 |
| Molecular Formula | C15H17ClF3N3O |
| Molecular Weight | 347.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 347.76 g/mol gives 5-(4-(4-Chloro-3-(trifluoromethyl)phenyl)piperazin-1-yl)pyrrolidin-2-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 5-(4-(4-Chloro-3-(trifluoromethyl)phenyl)piperazin-1-yl)pyrrolidin-2-one (CAS 91703-25-2), a certified reference material (molecular formula C15H17ClF3N3O, MW 347.76 g/mol) for analytical method development and quality control.
The molecular framework of 5-(4-(4-Chloro-3-(trifluoromethyl)phenyl)piperazin-1-yl)pyrrolidin-2-one (C15H17ClF3N3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H17ClF3N3O |
| Molecular Weight | 347.76 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 4-(3'-Chloro-5'-(trifluoromethyl)-3,6-dihydro-2H-[1,2'-bipyridin]-4-yl)morpholine (CAS 306977-22-0)
- 2-Chloro-1-[4-(3-nitrobenzenesulfonyl)piperazin-1-yl]ethan-1-one (CAS 1050909-55-1)
- 2-Chloro-1-(4-((4-nitrophenyl)sulfonyl)piperazin-1-yl)ethan-1-one (CAS 1087784-07-3)
- 1-[4-(3-Chloro-5-trifluoromethyl-pyridin-2-yl)-pyrimidin-2-ylsulfanyl]-propan-2-one (CAS 1311279-24-9)
- 2-chloro-N-(2-{[4-(trifluoromethyl)pyrimidin-2-yl]thio}phenyl)acetamide (CAS 646455-92-7)
- 5-Chloro-2-(methylthio)-N-(3-(trifluoromethyl)phenyl)pyrimidine-4-carboxamide (CAS 889768-92-7)
- Methyl 2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)thio)benzoate (CAS 385383-52-8)
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Recommended Standards
- 2-[(4-chlorophenyl)amino]-4-(3-cyanophenyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile (CAS 1347820-42-1)
- N-(4-Chlorophenyl)-3-{[(4-nitrobenzyl)oxy]imino}propanamide (CAS 477851-68-6)
- N-(2-Chlorophenyl)-2-(3-(2-fluorophenyl)-2-oxoimidazolidin-1-yl)acetamide (CAS 1251546-01-6)
- 4-((2-Acetoxy-5-chlorophenyl)carbamoyl)phenyl acetate (CAS 312746-89-7)
- 2-{[(2,4-dichlorophenyl)thio]methyl}-4,5,6,7-tetrafluorobenzo[b]furan (CAS 256525-93-6)
- 4,5-Difluoro-2-methoxybenzonitrile (CAS 425702-28-9)
- 3-Fluoro-6-hydroxypicolinonitrile (CAS 1807298-28-7)
- 1-(2,6-Dimethylpyrimidin-4-yl)piperidin-4-amine (CAS 893754-92-2)
- 2834-23-3 Chlorodifluoroacetic anhydride Acetic acid, 2-chloro-2,2-difluoro-, 1,1'-anhydride Acetic acid, chlorodifluoro-, anhydride EINECS 220-603-4 (CAS 2834-23-3)
- 1-((3-Chlorophenyl)thio)-3-(4-(2-fluorophenyl)piperazin-1-yl)propan-2-ol (CAS 338421-89-9)
- 4-methyl-1H-indazole-3-carboxylic acid (CAS 885518-90-1)
- 2-(7-Bromo-1H-benzo[d]imidazol-6-yl)acetonitrile (CAS 1803895-20-6)
- 2-(2-Methylmorpholino)isonicotinic acid hydrochloride (CAS 1354958-10-3)
- (Asn5)-Delta-Sleep Inducing Peptide (H-2555.0005) (CAS 80064-67-1)
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