1-(2-Chloro-6-fluorobenzyl)-1H-benzo[d]imidazole-2-thiol CAS 917749-44-1
| CAS No. | 917749-44-1 |
| Molecular Formula | C14H10ClFN2S |
| Molecular Weight | 292.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(2-Chloro-6-fluorobenzyl)-1H-benzo[d]imidazole-2-thiol (CAS 917749-44-1) is a high-purity analytical reference standard with the molecular formula C14H10ClFN2S and a molecular weight of 292.76 g/mol.
1-(2-Chloro-6-fluorobenzyl)-1H-benzo[d]imidazole-2-thiol (C14H10ClFN2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H10ClFN2S |
| Molecular Weight | 292.76 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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- Methyl 2-(2-bromoacetyl)benzoate (CAS 7460-55-1)
- 2-Amino-6-(methylthio)hexanoic acid (CAS 19185-25-2)
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- Cefadroxil Impurity 49 (CAS CATO-C4X-122449)
- Tetrapeptide-3 (CAS 827306-97-8)
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