5-Chloro-4-hydroxy-2-methoxybenzaldehyde CAS 917828-33-2
| CAS No. | 917828-33-2 |
| Molecular Formula | C8H7ClO3 |
| Molecular Weight | 186.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-Chloro-4-hydroxy-2-methoxybenzaldehyde (CAS 917828-33-2) is a high-purity analytical reference standard with the molecular formula C8H7ClO3 and a molecular weight of 186.59 g/mol.
The molecular framework of 5-Chloro-4-hydroxy-2-methoxybenzaldehyde (C8H7ClO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7ClO3 |
| Molecular Weight | 186.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 4-Chloro-2-(hydroxymethyl)benzoic acid (CAS 100448-59-7)
- Methyl 2-Chloro-4-hydroxybenzoate (CAS 104253-44-3)
- 3-Chloro-2,4-dihydroxy-6-methylbenzaldehyde (CAS 106325-72-8)
- 2-Chloro-4-(hydroxymethyl)benzoic acid (CAS 1071989-48-4)
- Methyl 2-chloro-3-hydroxybenzoate (CAS 1125632-11-2)
- 2-Chloro-6-hydroxy-4-methoxybenzaldehyde (CAS 116475-68-4)
- 2-Chloro-3-(hydroxymethyl)benzoic acid (CAS 1187238-13-6)
- 4-Chloro-3-(hydroxymethyl)benzoic acid (CAS 1187238-15-8)
Recommended Standards
- 5-Chloro-2-hydroxyphenylacetic Acid (CAS 24161-38-4)
- 6-Chloro-1,3-benzodioxole-5-methanol (CAS 2591-25-5)
- 5-Chloro-2-hydroxy-4-methylbenzoic acid (CAS 35458-35-6)
- 6-Chloro-2-hydroxy-3-methylbenzoic acid (CAS 872276-56-7)
- 4-Hydroxy-L-threonine (CAS 21768-45-6)
- (R)-1-Boc-amino-butyl-3-amine (CAS 1187927-71-4)
- 2-[4-(Methylthio)phenyl]ethylamine (CAS 118468-21-6)
- 6-Amino-5-(difluoromethyl)-4-iodonicotinic acid (CAS 1805137-88-5)
- (Z)-3-(4-Methoxypyridin-1-ium-1-yl)-1,4-dioxo-1,4-diphenylbut-2-ene-2-thiolate (CAS 2377723-52-7)
- Ethyl 4-Bromo-1,5-dimethyl-1H-pyrazole-3-carboxylate (CAS 5775-90-6)
- Tedizolid Impurity 37 (CAS 1239662-48-6)
- Tris(dimethylamino)arsine, 99% (CAS 6596-96-9)
- (1,1,2,3,3,3-Hexafluoropropoxy)pentafluorobenzene (CAS 845523-35-5)
- Semaglutide impurity 49 (CAS CATO-C4X-222649)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com