3-(5-Ethoxybenzo[d]thiazol-2-yl)-2-phenylquinazolin-4(3H)-one CAS 918154-66-2
| CAS No. | 918154-66-2 |
| Molecular Formula | C23H17N3O2S |
| Molecular Weight | 399.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(5-Ethoxybenzo[d]thiazol-2-yl)-2-phenylquinazolin-4(3H)-one is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(5-Ethoxybenzo[d]thiazol-2-yl)-2-phenylquinazolin-4(3H)-one (CAS 918154-66-2), molecular formula C23H17N3O2S and molecular weight 399.46 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(5-Ethoxybenzo[d]thiazol-2-yl)-2-phenylquinazolin-4(3H)-one (C23H17N3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H17N3O2S |
| Molecular Weight | 399.46 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Ethoxybenzo Standards
- 3-(4-Ethoxybenzo[d]thiazol-2-yl)-2-phenylquinazolin-4(3H)-one (CAS 918154-71-9)
- 3-(6-Ethoxybenzo[d]thiazol-2-yl)-2-phenylquinazolin-4(3H)-one (CAS 82450-46-2)
- N-(6-Ethoxybenzo[d]thiazol-2-yl)-2-(phenylsulfonyl)acetamide (CAS 823825-88-3)
- N-(6-Ethoxybenzo[d]thiazol-2-yl)-3,4-dimethylbenzenesulfonamide (CAS 438225-39-9)
- N-(6-Ethoxybenzo[d]thiazol-2-yl)-3,5-dimethoxybenzamide (CAS 300712-78-1)
- 5-(((6-Ethoxybenzo[d]thiazol-2-yl)amino)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione (CAS 1023845-26-2)
- 1-(4-(6-Ethoxybenzo[d]thiazol-2-yl)piperazin-1-yl)pentan-1-one (CAS 897470-72-3)
- N-(4-Ethoxybenzo[d]thiazol-2-yl)-2-(methylthio)benzamide (CAS 896344-39-1)
Recommended Standards
- 3-((4-Fluorophenyl)sulfonyl)-N-(2-(phenylsulfonyl)ethyl)propanamide (CAS 337923-49-6)
- 4-(4-Hydroxy-3-methoxyphenyl)-5-(3-methoxypropyl)-3-(thiophen-2-yl)-4,5-dihydropyrrolo[3,4-c]pyrazol-6(1H)-one (CAS 939742-60-6)
- 2,4,6-Tris(4-methoxyphenyl)pyrylium (CAS 47659-08-5)
- 4-Methoxy-N-(3-{7-thia-2,5-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),3,5,9,11-pentaen-4-yl}phenyl)benzamide (CAS 685107-39-5)
- 8-Nitro-7-oxo-7,10-dihydro-1,10-phenanthroline-3-carboxylic acid (CAS 223664-42-4)
- 4-(Methoxycarbonyl)-2-(pyrrolidine-1-carbonyl)furan-3-carboxylic acid (CAS 5165-13-9)
- 1-(2-iodoethoxy)-2-methoxy-ethane (CAS 104539-21-1)
- Dichloro[(S)-(-)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl][(S)-(-)-2-(α-methylmethanamine)-1H-benzimidazole]ruthenium(II) (CAS 1443051-87-3)
- Spiro[1-azabicyclo[2.2.2]octane-3,5′(4′H)-oxazol]-2′-amine (CAS 138272-87-4)
- 878748-66-4 1-Benzyl-2-(chloromethyl)-1H-benzimidazole--hydrogen chloride (1/1) DTXSID10495221 (CAS 878748-66-4)
- 5-(4-Fluorophenyl)-4,5-dihydrothieno[2,3-d]pyridazine (CAS 303145-59-7)
- 4-(2-Phenylacetyl)-1H-pyrrole-2-carboxylic acid (CAS 478249-37-5)
- 1,3-Benzenedicarboxylic acid, polymer with 12-aminododecanoic acid and 1,4-butanediol (CAS 73003-20-0)
- Galanin-Like Peptide (rat) trifluoroacetate salt (CAS 245114-97-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com