2-(3-Iodo-2H-pyrazolo[3,4-b]pyridin-2-yl)acetic acid CAS 918485-17-3

Description

Compared with other compounds in its class, the molecular weight of 303.06 g/mol gives 2-(3-Iodo-2H-pyrazolo[3,4-b]pyridin-2-yl)acetic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-(3-Iodo-2H-pyrazolo[3,4-b]pyridin-2-yl)acetic acid (CAS 918485-17-3), molecular formula C8H6IN3O2 and molecular weight 303.06 g/mol, is a CATO reference standard with documented purity and traceability.

2-(3-Iodo-2H-pyrazolo[3,4-b]pyridin-2-yl)acetic acid (C8H6IN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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