5-Fluoro-2-(piperidin-4-yloxy)pyridine CAS 918535-95-2
| CAS No. | 918535-95-2 |
| Molecular Formula | C10H13FN2O |
| Molecular Weight | 196.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-Fluoro-2-(piperidin-4-yloxy)pyridine (CAS 918535-95-2), molecular formula C10H13FN2O and molecular weight 196.22 g/mol, is a CATO reference standard with documented purity and traceability.
5-Fluoro-2-(piperidin-4-yloxy)pyridine (C10H13FN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 5-Fluoro-2-(piperidin-4-yloxy)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H13FN2O |
| Molecular Weight | 196.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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- 3-(4-Fluoro-3,5-dimethylphenyl)propanoic acid (CAS 1017779-63-3)
- 1-(3-Fluoro-4-isopropoxyphenyl)ethan-1-one (CAS 1019478-62-6)
- 3-Fluoro-4-isobutoxybenzaldehyde (CAS 1021231-45-7)
- 2-Fluoro-5-phenylpentanoic acid (CAS 1071002-03-3)
- 2-(4-Fluoro-3-methylphenyl)butanoic acid (CAS 1082507-45-6)
- 1-(5-Fluoro-2-methoxyphenyl)butan-1-one (CAS 1094648-11-9)
- 1-(5-Fluoro-2-methoxyphenyl)-2-methylpropan-1-one (CAS 1094748-74-9)
- 5-Fluoro-2-isobutoxybenzaldehyde (CAS 1096786-34-3)
Recommended Standards
- 5-Fluoro-2-(1-piperidinyl)-4-pyrimidinylamine (CAS 247225-85-0)
- 5-Fluoro-2-[(1-methylpyrrolidin-3-yl)oxy]pyridine (CAS 2198986-75-1)
- 4-Fluoro-3-methyl (1,3-dioxolan-2-ylmethyl)benzene (CAS 898785-07-4)
- 5-Fluoro-2-methyl (1,3-dioxolan-2-ylmethyl)benzene (CAS 898785-10-9)
- Acetamide, N-(2-bromo-5-pyrimidinyl)- (CAS 1209458-44-5)
- 6,7-Dihydroimidazo[1,5-a]pyrazin-8(5H)-one (CAS 951626-36-1)
- Ethyl 3-oxo-3-(piperidin-2-yl)propanoate (CAS 70883-14-6)
- 2-{[(2-chlorophenyl)methyl]sulfanyl}-5-[3-(trifluoromethyl)phenyl]pyrimidine (CAS 339101-97-2)
- Benzyl (5-azaspiro[2.4]Heptan-1-yl)carbamate hydrochloride (CAS 1707602-66-1)
- (S)-2-amino-2-(3-chloro-4-(trifluoromethyl)phenyl)ethan-1-ol (CAS 1212810-68-8)
- ([1,2,4]Triazolo[4,3-a]pyridin-3-ylmethyl)amine hydrochloride (CAS 1314394-12-1)
- 2-Deoxy-8-(1-pyrenylamino)guanosine (CAS 85989-43-1)
- 5,6-Dihydroxy-4(3H)-pyrimidinone (CAS 98020-41-8)
- Des-Gly29,30-Tirzepatide (CAS CATO-CPTD788944)
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