5-Acetyl-3-((4-fluorophenyl)thio)-4-methyl-2H-[1,4'-bipyridin]-2-one CAS 918542-97-9
| CAS No. | 918542-97-9 |
| Molecular Formula | C19H15FN2O2S |
| Molecular Weight | 354.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Acetyl-3-((4-fluorophenyl)thio)-4-methyl-2H-[1,4'-bipyridin]-2-one (CAS 918542-97-9), molecular formula C19H15FN2O2S and molecular weight 354.40 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C19H15FN2O2S, 5-Acetyl-3-((4-fluorophenyl)thio)-4-methyl-2H-[1,4'-bipyridin]-2-one contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 354.40 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Acetyl-3-((4-fluorophenyl)thio)-4-methyl-2H-[1,4'-bipyridin]-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H15FN2O2S |
| Molecular Weight | 354.40 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Acetyl Standards
- 3-(2-Fluorophenyl)-4-((3-(2-methoxyphenyl)allylidene)amino)-1H-1,2,4-triazole-5(4H)-thione (CAS 677305-82-7)
- 5-Acetyl-3-((4-fluorophenyl)thio)-4-methyl-2H-[1,2'-bipyridin]-2-one (CAS 918542-91-3)
- 5-Acetyl-3-((4-fluorophenyl)thio)-4-methyl-2H-[1,3'-bipyridin]-2-one (CAS 918542-22-0)
- Ethyl 3-[(4-fluorophenyl)sulfanyl]-6-phenyl-4-pyridazinecarboxylate (CAS 338753-16-5)
- 4-(4-Fluorophenyl)-1-(4-(3-fluorophenyl)thiazol-2-yl)-1H-pyrazol-5-amine (CAS 955976-89-3)
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- N-(4-fluorophenyl)-4-hydroxy-1-methyl-1H-thieno[3,2-c][1,2]thiazine-3-carboxamide 2,2-dioxide (CAS 303987-81-7)
- (3-Fluorophenyl)(9-(pyrimidin-2-yl)-3,9-diazaspiro[5.5]undecan-3-yl)methanone (CAS 959517-65-8)
Recommended Standards
- 5-Benzyl-1,2-diphenylpyrimidine-4,6(1H,5H)-dione (CAS 61656-76-6)
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- 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methyl-8-(3-methylbut-2-en-1-yl)chroman-4-one (CAS 261776-60-7)
- 6-Hydroxy-5-((4-(4-methoxyphenyl)piperazin-1-yl)methyl)-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 439095-50-8)
- 4,6-Dihydro-1H-furo[3,4-c]pyrazole-3-carboxylic acid (CAS 1417985-33-1)
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- 2-(4-Fluorophenylamino)naphtho[2,3-d]thiazole-4,9-dione (CAS 220333-06-2)
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- Methyl benzylprolinate (CAS 201406-78-2)
- 3-hydroxy-4-[(4-methylphenyl)diazenyl]-2-naphthoic acid 82896-77-3 (CAS 82896-77-3)
- 4-Allyl-5-{[3-(trifluoromethyl)phenoxy]methyl}-4H-1,2,4-triazole-3-thiol (CAS 862652-27-5)
- Semaglutide impurity 259 (CAS CATO-C4X-2226259)
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