5-(3-Fluoro-4-methylphenyl)isoxazole-3-carboxylic acid CAS 919238-03-2
| CAS No. | 919238-03-2 |
| Molecular Formula | C11H8FNO3 |
| Molecular Weight | 221.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 5-(3-Fluoro-4-methylphenyl)isoxazole-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
5-(3-Fluoro-4-methylphenyl)isoxazole-3-carboxylic acid (CAS 919238-03-2) is a high-purity analytical reference standard with the molecular formula C11H8FNO3 and a molecular weight of 221.18 g/mol.
The molecular framework of 5-(3-Fluoro-4-methylphenyl)isoxazole-3-carboxylic acid (C11H8FNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H8FNO3 |
| Molecular Weight | 221.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 2-fluoro-5-methoxy-4-nitro-benzoic acid (CAS 1001345-80-7)
- 3-(4-Fluoro-3-methylphenyl)isoxazole-5-carboxylic acid (CAS 1018648-23-1)
- 5-Fluoro-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 1065093-99-3)
- 8-Fluoro-4-hydroxy-5-methylquinoline-3-carboxylic acid (CAS 1065094-00-9)
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Recommended Standards
- 4-methoxy-3-(2,2,2-trifluoroethoxy)aniline (CAS 953744-38-2)
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- 6-Fluoro-1-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 2264-33-7)
- 3-[(cyclopropylamino)sulfonyl]-4-methoxybenzoic acid (CAS 716358-76-8)
- 5-(1-Cyanocyclobutyl)-2-fluorophenylboronic acid (CAS 2096339-45-4)
- Gadolinium 156 (CAS 14392-07-5)
- [1-(3-Fluoro-4-morpholin-4-ylphenyl)ethyl]-methylamine hydrochloride (CAS 1332531-48-2)
- Methyl 4-(4-chlorophenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 134141-11-0)
- 4-Methyl-1-((2-methylbenzyl)thio)thieno[2,3-e][1,2,4]triazolo[4,3-a]pyrimidin-5(4H)-one (CAS 1189984-73-3)
- n-Ethyl-3-fluoro-4-methoxybenzenesulfonamide (CAS 915907-72-1)
- 6-(methylsulfanyl)-2,3-dihydro-1H-indole-2,3-dione (CAS 59868-43-8)
- Methyl 3-(5-fluoro-2-nitrophenyl)propanoate (CAS 1493774-33-6)
- Liraglutide Impurity 22 (CAS 536721-25-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com