1-Cyclopropyl-N-((5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)methyl)methanamine CAS 919347-13-0
| CAS No. | 919347-13-0 |
| Molecular Formula | C16H25BN2O2 |
| Molecular Weight | 288.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Cyclopropyl-N-((5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)methyl)methanamine.
1-Cyclopropyl-N-((5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)methyl)methanamine (CAS 919347-13-0), molecular formula C16H25BN2O2 and molecular weight 288.19 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-Cyclopropyl-N-((5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)methyl)methanamine (C16H25BN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-Cyclopropyl-N-((5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)methyl)methanamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H25BN2O2 |
| Molecular Weight | 288.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
Related Cyclopropyl Standards
- N-Cyclopropyl-N,3-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine (CAS 1350637-54-5)
- N1-Cyclopropyl-N2-(4-(trifluoromethoxy)phenyl)oxalamide (CAS 941939-12-4)
- N-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinamide (CAS 1201644-52-1)
- N-Cyclopropyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinamide (CAS 2096333-89-8)
- 2-Cyclopropyl-6-phenyl-4-(trifluoromethyl)nicotinonitrile (CAS 478081-24-2)
- 4-Cyclopropyl-3-iodobenzoic acid (CAS 1131588-02-7)
- Methyl 2-((2-cyclopropyl-3-formylbenzofuran-5-yl)oxy)propanoate (CAS 1211249-98-7)
- ethyl {[4-cyclopropyl-6-(difluoromethyl)pyrimidin-2-yl]thio}acetate (CAS 886498-18-6)
Recommended Standards
- 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperazine (CAS 912369-50-7)
- 2-(Piperidin-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 852228-08-1)
- (E)-2-Methyl-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)but-3-en-2-ol (CAS 2129163-43-3)
- 3-(1-Piperazinyl)phenylboronic Acid Pinacol Ester (CAS 871125-87-0)
- (4Z)-N1,N1-Dimethyl-N4-{1-[2-(pyridin-4-yl)-1,3-thiazol-5-yl]ethylidene}benzene-1,4-diamine (CAS 1212789-93-9)
- Ethyl 4-(propylamino)piperidine-1-carboxylate (CAS 1020984-28-4)
- 2-methyl-1-(4-(trifluoromethyl)phenyl)propan-2-amine (CAS 459-00-7)
- 3-((1-Methoxypropan-2-yl)oxy)-2,2-dimethylpropane-1-sulfonyl chloride (CAS 1469056-89-0)
- tert-Butyl 3-((tert-butoxycarbonyl)amino)-3-cyanopyrrolidine-1-carboxylate (CAS 1364663-43-3)
- 2-(Aminomethyl)-3-(difluoromethyl)-4-hydroxy-5-methoxypyridine (CAS 1805544-73-3)
- 21-Bromo-progesterone (CAS 26987-66-6)
- Ethyl 5-(5-bromopyridin-2-yl)-3-methylisoxazole-4-carboxylate (CAS 1311280-10-0)
- (2R,3R,4S,5R)-2-(2-(4-(Cyclopentylmethyl)-1H-1,2,3-triazol-1-yl)-6-(methylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS 918868-03-8)
- Peptide Impurity 82 (CAS 10491-78-8)
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