Ethyl 2-oxo-1,2-dihydropyrimidine-5-carboxylate hydrobromide CAS 91978-81-3
| CAS No. | 91978-81-3 |
| Molecular Formula | C7H8N2O3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 2-oxo-1,2-dihydropyrimidine-5-carboxylate hydrobromide.
CATO supplies Ethyl 2-oxo-1,2-dihydropyrimidine-5-carboxylate hydrobromide (CAS 91978-81-3), a certified reference material (molecular formula C7H8N2O3HBr, MW 249.06 g/mol) for analytical method development and quality control.
Ethyl 2-oxo-1,2-dihydropyrimidine-5-carboxylate hydrobromide (C7H8N2O3HBr) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 2-oxo-1,2-dihydropyrimidine-5-carboxylate hydrobromide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H8N2O3 HBr |
| Molecular Weight | 249.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- 9-([1,1'-Biphenyl]-4-yl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9H-carbazole (CAS 1427213-44-2)
- 2-(1H-pyrazol-1-yl)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1186115-51-4)
- 4-allyl-4-fluorocyclohexa-2,5-dien-1-one (CAS 738614-29-4)
- 2-(3,5-Dimethyl-1H-pyrazol-1-yl)-3-(trifluoromethyl)quinoxaline (CAS 321538-05-0)
- 1-Bromo-4-(1-ethynylcyclopropyl)benzene (CAS 1378873-54-1)
- 4-(3-(tert-Butyl)-5-methylphenyl)-1H-pyrazol-3-amine hydrochloride (CAS 1177349-64-2)
- Sitagliptin Impurity 69 (CAS CATO-C4X-114469)
- 4-Methylfuran-2-carbonyl Chloride (CAS 39272-49-6)
- (2-Propylphenyl)methanol (CAS 17475-43-3)
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