[1,2,4]Triazolo[4,3-a]pyridin-3-ylmethanamine dihydrochloride CAS 91981-60-1
| CAS No. | 91981-60-1 |
| Molecular Formula | C7H8N4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), [1,2,4]Triazolo[4,3-a]pyridin-3-ylmethanamine dihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
[1,2,4]Triazolo[4,3-a]pyridin-3-ylmethanamine dihydrochloride (CAS 91981-60-1) is a high-purity analytical reference standard with the molecular formula C7H8N4HCl and a molecular weight of 184.63 g/mol.
The molecular framework of [1,2,4]Triazolo[4,3-a]pyridin-3-ylmethanamine dihydrochloride (C7H8N4HCl) is characterized by a nitrile group, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H8N4 2*HCl |
| Molecular Weight | 184.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Triazolo Standards
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- 3-Methyl-[1,2,4]triazolo[4,3-a]pyridine (CAS 1004-65-5)
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- 4-(Methoxymethyl)benzene-1-thiol (CAS 93825-16-2)
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