4-Chloro-2-(trichloromethyl)-6-(trifluoromethyl)quinoline CAS 91991-82-1
| CAS No. | 91991-82-1 |
| Molecular Formula | C11H4Cl4F3N |
| Molecular Weight | 348.96 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-Chloro-2-(trichloromethyl)-6-(trifluoromethyl)quinoline (C11H4Cl4F3N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 4-Chloro-2-(trichloromethyl)-6-(trifluoromethyl)quinoline (CAS 91991-82-1), a certified reference material (molecular formula C11H4Cl4F3N, MW 348.96 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Chloro-2-(trichloromethyl)-6-(trifluoromethyl)quinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H4Cl4F3N |
| Molecular Weight | 348.96 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 7-Chloro-2-methyl-N-(3-(triethylsilyl)propyl)quinolin-4-amine (CAS 62619-95-8)
- 3-(3-(4-Chloro-3,5-dimethyl-1h-pyrazol-1-yl)propyl)-2-thioxo-2,3-dihydroquinazolin-4(1h)-one (CAS 1006491-78-6)
- (E)-4-chloro-N'-((2-(piperidin-1-yl)thiazol-5-yl)methylene)benzohydrazide (CAS 477854-97-0)
- 2-Chloro-n-[3-(diethylsulfamoyl)-4-ethoxyphenyl]acetamide (CAS 923773-99-3)
- 3-chloro-9-tosyl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-one (CAS CATO-C3D-262252)
- 1-(3-Chloro-2-methylphenyl)-3-(1-(3-methyl-1,2,4-oxadiazol-5-yl)cyclohexyl)urea (CAS 1396765-53-9)
- 2-(5-((2-Chloro-6-fluorobenzyl)thio)-4-ethyl-4H-1,2,4-triazol-3-yl)pyridine (CAS 577787-21-4)
- 2-[(5-Chloro-1,3-dimethyl-1H-pyrazol-4-yl)formamido]-N-[4-(propan-2-yl)phenyl]acetamide (CAS 955976-68-8)
Recommended Standards
- 4-Bromo-5-iodonaphthalen-2-ol (CAS 2763158-20-7)
- 3-(4-Bromophenyl)-4-iodo-1H-pyrazole (CAS 1342385-37-8)
- rac 1-Palmitoyl-2-chloropropanediol (CAS 63326-63-6)
- 6-Bromo-4-iodoisoquinolin-3-amine (CAS 2143040-26-8)
- 5-fluorothiazolo[5,4-b]pyridin-2-amine (CAS 865663-86-1)
- 2-Amino-4,6-dichloronicotinonitrile (CAS 53815-34-2)
- (S)-1-(1-phenylethyl)urea (CAS 25144-64-3)
- 1-(tert-Butoxycarbonyl)-3-oxopiperidine-2-carboxylic acid (CAS 1273577-08-4)
- 2-Chloro-N-((5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl)methyl)-N-isopropylacetamide (CAS 873790-29-5)
- 3,5-Bis(chloromethyl)-1H-pyrazole hydrochloride (CAS 96616-82-9)
- 2-((4-Methyl-5-(m-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N-(perfluorophenyl)acetamide (CAS 882749-27-1)
- 7-Amino-14-Azadispiro[5.1.5.2]pentadecan-15-one (CAS 34106-77-9)
- 1,1',1''-((2,4,6-Trimethylbenzene-1,3,5-triyl)tris(methylene))tris(4-cyanopyridin-1-ium)bromide (CAS 247095-17-6)
- Semaglutide impurity 248 (CAS CATO-C4X-2226248)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com