1H-Imidazo[4,5-c]pyridine-2-carboxylic acid CAS 91996-99-5
| CAS No. | 91996-99-5 |
| Molecular Formula | C7H5N3O2 |
| Molecular Weight | 163.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1H-Imidazo[4,5-c]pyridine-2-carboxylic acid (CAS 91996-99-5) is a high-purity analytical reference standard with the molecular formula C7H5N3O2 and a molecular weight of 163.13 g/mol.
1H-Imidazo[4,5-c]pyridine-2-carboxylic acid (C7H5N3O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1H-Imidazo[4,5-c]pyridine-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5N3O2 |
| Molecular Weight | 163.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Nitrogen Atoms | 3 |
Related H Standards
- 1H-Imidazo[4,5-b]pyridine-5-carboxylic Acid (CAS 1019108-05-4)
- Imidazo[1,2-a]pyrazine-8-carboxylic acid (CAS 1029144-45-3)
- Imidazo[1,5-a]pyrimidine-8-carboxylic acid (CAS 1083282-02-3)
- Imidazo[1,2-b]pyridazine-8-carboxylic acid (CAS 1159977-66-8)
- 3H-Imidazo[4,5-c]pyridine-6-carboxylic acid (CAS 1211590-38-3)
- Imidazo[1,2-b]pyridazine-3-carboxylic Acid (CAS 1308384-58-8)
- Imidazo[1,5-a]pyrazine-3-carboxylic acid (CAS 1517097-34-5)
- Imidazo[1,2-a]pyrazine-2-carboxylic Acid (CAS 77112-53-9)
Recommended Standards
- 1H-Benzo[d][1,2,3]triazole-1-carboxylic acid (CAS 60932-58-3)
- 1H-Pyrazolo[3,4-b]pyridine-5-carboxylic Acid (CAS 952182-02-4)
- 1H-1,2,3-Benzotriazole-7-carboxylic Acid (CAS 62972-61-6)
- 1-Nitroimidazo[1,5-a]pyridine (CAS 75427-23-5)
- methyl 2-(2-bromo-2-methylpropanamido)-2-methylpropanoate (CAS 151142-96-0)
- 2-Bromo-4,5-dichloropyrimidine (CAS 1806851-15-9)
- TERT-BUTYL 1H-INDOLE-6-CARBOXYLATE (CAS 199589-62-3)
- 1-Pivaloyl-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine-6-carbonitrile (CAS 1228666-61-2)
- Methyl Dichloroacetate (CAS 116-54-1)
- 3-Chloro-4-(2-methyl-1H-imidazol-1-yl)aniline (CAS 758636-23-6)
- 9- Anthraceneacetonitri le (CAS 2961-76-4)
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