N-(5-Chloro-2,4-dimethoxyphenyl)-3-hydroxy-2-naphthylcarboxamide CAS 92-72-8
| CAS No. | 92-72-8 |
| Molecular Formula | C19H16ClNO4 |
| Molecular Weight | 357.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(5-Chloro-2,4-dimethoxyphenyl)-3-hydroxy-2-naphthylcarboxamide.
N-(5-Chloro-2,4-dimethoxyphenyl)-3-hydroxy-2-naphthylcarboxamide (CAS 92-72-8) is a high-purity analytical reference standard with the molecular formula C19H16ClNO4 and a molecular weight of 357.79 g/mol.
Structurally, N-(5-Chloro-2,4-dimethoxyphenyl)-3-hydroxy-2-naphthylcarboxamide (C19H16ClNO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 357.79 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H16ClNO4 |
| Molecular Weight | 357.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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- 1-(4-Chloro-7-methoxyquinolin-2-yl)-3-(4-methoxyphenyl)urea (CAS 195133-49-4)
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Recommended Standards
- Indomethacine (CAS 53-86-1)
- Pyraclostrobin-desmethoxy (CAS 512165-96-7)
- Roxadustat Impurity 149 (CAS CATO-C4X-2213149)
- 3-Chloro-α-[(4-methylphenyl)sulfonyl]-2-quinoxalineacetonitrile (CAS 121512-59-2)
- 5-cyano-1H-indole-3-carboxylic acid (CAS 174500-89-1)
- Methyl 6-amino-3-fluoropicolinate (CAS 1446509-50-7)
- 3-CHloro-n-cyclopropyl-2-fluorobenzamide (CAS 1503589-53-4)
- Ethyl 4-amino-3-(5-chloro-2-methoxyphenyl)-2-thioxo-2,3-dihydrothiazole-5-carboxylate (CAS 688337-73-7)
- 2-Bromo-4-ethyl pyridine 2-bromo-4-ethylpyridine 54453-91-7 (CAS 54453-91-7)
- 3-Chloro-5-(methanesulfonylmethyl)-4h-1,2,4-triazole (CAS 1343395-09-4)
- Methyl 2-Amino-6-fluoro-3-nitrobenzoate (CAS 346691-23-4)
- Faropenem Impurity 83 (CAS CATO-C4X-128983)
- 1-(4-Bromo-2-fluorobenzyl)-4-methylpiperidine (CAS 1251252-63-7)
- D-[Ala]24-Semaglutide (CAS CATO-C4X-2226126)
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