5-Bromospiro[indoline-3,4'-piperidin]-2-one CAS 920023-50-3
| CAS No. | 920023-50-3 |
| Molecular Formula | C12H13BrN2O |
| Molecular Weight | 281.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 5-Bromospiro[indoline-3,4'-piperidin]-2-one (CAS 920023-50-3), a certified reference material (molecular formula C12H13BrN2O, MW 281.15 g/mol) for analytical method development and quality control.
5-Bromospiro[indoline-3,4'-piperidin]-2-one (C12H13BrN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 5-Bromospiro[indoline-3,4'-piperidin]-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H13BrN2O |
| Molecular Weight | 281.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromospiro Standards
- 6-Bromospiro[indoline-3,4'-piperidin]-2-one (CAS 1160248-48-5)
- 6-Bromospiro[1,2,3,4-tetrahydroquinazoline-2,1’-cyclopentane]-4-one (CAS 1272756-17-8)
- 7-Bromospiro[indoline-3,4'-piperidin]-2-one (CAS 1395071-05-2)
- 4-Bromospiro[indoline-3,4'-piperidin]-2-one (CAS 1713164-01-2)
- 6-Bromospiro[isoquinoline-4,3'-oxetane]-1,3-dione (CAS 2892253-41-5)
- 6'-Bromospiro[cyclohexane-1,3'-indolin]-2'-one (CAS 1190866-02-4)
- 5'-Bromospiro[cyclohexane-1,3'-indolin]-2'-one (CAS 304468-42-6)
- 6-Bromospiro[chromane-2,4'-piperidine] (CAS 945722-86-1)
Recommended Standards
- 5-Bromo-2-(piperidin-3-yl)benzo[d]oxazole (CAS 885275-09-2)
- 8-Bromofluoranthene (CAS 2969-58-6)
- 5-Bromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)-4-methoxypyridine (CAS 2311866-08-5)
- Methyl 2-bromo-6,7-dihydro-5H-benzo[7]annulene-8-carboxylate (CAS 229007-63-0)
- 4-(2,6-Dimethylphenyl)-N,N-dimethylpiperazine-1-sulfonamide (CAS 723740-41-8)
- 1,2,6,7-DIEPOXYHEPTANE (CAS 4247-19-2)
- 3-(3-Methoxyphenoxy)propanenitrile (CAS 6279-84-1)
- n-Cyclobutyl-2,5-dimethylaniline (CAS 1250615-09-8)
- (5-(4-Bromophenyl)isoxazol-3-yl)methanol (CAS 640291-96-9)
- 4-Amino-1-(4-methoxyphenyl)-1H-pyrazole-3-carbonitrile (CAS 1426541-61-8)
- Mepiquat-d16 Chloride (CAS 24307-26-4(Unlabeled))
- Tert-butyl 5-oxo-5H-spiro[furo[3,4-b]pyridine-7,4'-piperidine]-1'-carboxylate (CAS 1187829-86-2)
- 2-Methoxy-n,5-dimethylbenzenesulfonamide (CAS 675864-78-5)
- Peptide Impurity 09 X TFA Salt (CAS CATO-CPTD788809)
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