7-Chloro-2-(4-chlorophenyl)-6-methylquinoline-4-carboxylic acid CAS 920278-18-8
| CAS No. | 920278-18-8 |
| Molecular Formula | C17H11Cl2NO2 |
| Molecular Weight | 332.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 332.18 g/mol gives 7-Chloro-2-(4-chlorophenyl)-6-methylquinoline-4-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
7-Chloro-2-(4-chlorophenyl)-6-methylquinoline-4-carboxylic acid (CAS 920278-18-8) is a high-purity analytical reference standard with the molecular formula C17H11Cl2NO2 and a molecular weight of 332.18 g/mol.
The molecular framework of 7-Chloro-2-(4-chlorophenyl)-6-methylquinoline-4-carboxylic acid (C17H11Cl2NO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H11Cl2NO2 |
| Molecular Weight | 332.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 6-Chloro-2-(2-methoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-29-5)
- 6-Chloro-2-(3-methoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-30-8)
- 6-Chloro-2-(4-methoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-31-9)
- 8-Chloro-2-(4-methoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-65-9)
- 8-Chloro-2-(3-methoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-67-1)
- 8-Chloro-2-(2-methoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-69-3)
- 3-Acetyl-6-chloro-4-(4-chlorophenyl)quinolin-2(1H)-one (CAS 1283108-77-9)
- (2E)-3-(3-Chloro-4-methoxyphenyl)-2-[(E)-2-chlorobenzoyl]prop-2-enenitrile (CAS 861207-91-2)
Recommended Standards
- 7-Chloro-2-(3-chlorophenyl)-8-methylquinoline-4-carboxylic acid (CAS 725244-74-6)
- 7-Chloro-2-(4-chlorophenyl)-8-methylquinoline-4-carboxylic acid (CAS 500356-69-4)
- 7-Chloro-2-(2-chlorophenyl)-8-methylquinoline-4-carboxylic acid (CAS 725221-35-2)
- 8-Chloro-2-(3-chlorophenyl)-3-methylquinoline-4-carboxylic acid (CAS 862677-10-9)
- 2-(4-Fluorophenyl)-1-{4-[6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl}ethan-1-one (CAS 1775544-36-9)
- 6-Methoxyisoquinoline-1-carboxylic acid (CAS 1179148-81-2)
- 3-(thiophen-3-yl)piperidine hydrochloride (CAS 1185077-50-2)
- (S)-5-((Trityloxy)methyl)dihydrofuran-2(3H)-one (CAS 73968-62-4)
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- (3-(Benzyloxy)-4-methoxybenzyl)triphenylphosphonium chloride (CAS 51458-25-4)
- 53116-81-7 Tetrakis(N,N,N-trimethylmethanaminium) orthosilicate DTXSID50746209 (CAS 53116-81-7)
- N-Ethyl-1-methyl-1H-benzo[d]imidazol-2-amine (CAS 98711-68-3)
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