3-((4-Fluorobenzyl)thio)-6-(4-methoxyphenyl)pyridazine CAS 920453-86-7
| CAS No. | 920453-86-7 |
| Molecular Formula | C18H15FN2OS |
| Molecular Weight | 326.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-((4-Fluorobenzyl)thio)-6-(4-methoxyphenyl)pyridazine (CAS 920453-86-7), molecular formula C18H15FN2OS and molecular weight 326.39 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-((4-Fluorobenzyl)thio)-6-(4-methoxyphenyl)pyridazine (C18H15FN2OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H15FN2OS |
| Molecular Weight | 326.39 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Fluorobenzyl Standards
- N1-(4-Fluorobenzyl)-N2-((3-methoxytetrahydrothiophen-3-yl)methyl)oxalamide (CAS 1448045-21-3)
- 3-((3-Fluorobenzyl)thio)-6-(3-methoxyphenyl)pyridazine (CAS 921057-10-5)
- 3-((3-Fluorobenzyl)thio)-6-(4-methoxyphenyl)pyridazine (CAS 921164-16-1)
- 6-(4-(4-Fluorobenzyl)piperazin-1-yl)-3-methyl-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1333730-26-9)
- N-(3-Fluorobenzyl)-2-iodoaniline (CAS 1039834-40-6)
- N-(4-Fluorobenzyl)-4-iodoaniline (CAS 1040018-16-3)
- N-(3-Fluorobenzyl)-4-iodoaniline (CAS 1040064-37-6)
- N-(4-Fluorobenzyl)-2-iodoaniline (CAS 1040308-57-3)
Recommended Standards
- 3-(2-Ethylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole (CAS 71368-30-4)
- 3-(4-(Pentyloxy)benzoyl)phenyl acetate (CAS 890100-06-8)
- 2-Methoxy-4-((2S,3R)-7-methoxy-3-methyl-5-((E)-prop-1-en-1-yl)-2,3-dihydrobenzofuran-2-yl)phenol (CAS 83377-50-8)
- 3-(4-Methoxyphenyl)-1,5-diphenyl-1H-pyrazole (CAS 33045-40-8)
- 5-(1,3-dioxolan-2-yl)-1,3-thiazole-2-carbaldehyde (CAS 1803203-53-3)
- 4-(4-Bromophenyl)-5-(ethylsulfonyl)pyrimidin-2-amine (CAS 1713714-45-4)
- 6-Bromo-4-(difluoromethyl)-5-methylpyridine-2-sulfonamide (CAS 1804955-43-8)
- 1-(4-Methoxyphenyl)-3-(methylamino)azetidin-2-one (CAS 1706651-37-7)
- AvrainvillamideDISCONTINUED (CAS 269741-97-1)
- N-((6-Bromopyridin-3-yl)methyl)-2-chloro-N-cyclopropylacetamide (CAS 1353982-76-9)
- 3-(Furan-3-yl)-4-methyl-1h-pyrazol-5-amine (CAS 1311185-34-8)
- 3-Methyl-1,2,3,7-tetrahydropyrazolo[1,5-a]pyrimidin-6-amine (CAS 439902-01-9)
- Zidebactam (CAS 1436861-97-0)
- Tirzepatide Impurity 45 (CAS CATO-C4X-324045)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com