2-(1-Methyl-2,4-dioxo-5-propoxy-1,4-dihydropyrido[2,3-d]pyrimidin-3(2H)-yl)acetamide CAS 921480-54-8

Purity 97%+In StockPharmaceutical Standards
CAS No.921480-54-8
Molecular FormulaC13H16N4O4
Molecular Weight292.29 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(1-Methyl-2,4-dioxo-5-propoxy-1,4-dihydropyrido[2,3-d]pyrimidin-3(2H)-yl)acetamide CAS 921480-54-8 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

2-(1-Methyl-2,4-dioxo-5-propoxy-1,4-dihydropyrido[2,3-d]pyrimidin-3(2H)-yl)acetamide (CAS 921480-54-8), molecular formula C13H16N4O4 and molecular weight 292.29 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-(1-Methyl-2,4-dioxo-5-propoxy-1,4-dihydropyrido[2,3-d]pyrimidin-3(2H)-yl)acetamide (C13H16N4O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

As a certified reference material (CRM), 2-(1-Methyl-2,4-dioxo-5-propoxy-1,4-dihydropyrido[2,3-d]pyrimidin-3(2H)-yl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC13H16N4O4
Molecular Weight292.29 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Nitrogen Atoms4

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