6-Bromospiro[chroman-2,4'-piperidin]-4-one hydrochloride CAS 921760-46-5
| CAS No. | 921760-46-5 |
| Molecular Formula | C13H14BrNO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Bromospiro[chroman-2,4'-piperidin]-4-one hydrochloride.
CATO supplies 6-Bromospiro[chroman-2,4'-piperidin]-4-one hydrochloride (CAS 921760-46-5), a certified reference material (molecular formula C13H14BrNO2HCl, MW 332.62 g/mol) for analytical method development and quality control.
The molecular framework of 6-Bromospiro[chroman-2,4'-piperidin]-4-one hydrochloride (C13H14BrNO2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6-Bromospiro[chroman-2,4'-piperidin]-4-one hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H14BrNO2 HCl |
| Molecular Weight | 332.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromospiro Standards
- 2-bromospiro[3.3]heptane (CAS 102115-82-2)
- 2'-Bromospiro[[1,3]dithiolane-2,9'-fluorene] (CAS 113425-37-9)
- 5'-Bromospiro[[1,3]dithiolane-2,3'-indolin]-2'-one (CAS 113549-10-3)
- 5'-Bromospiro[cyclopentane-1,3'-indoline] (CAS 1160247-93-7)
- 6-Bromospiro[indoline-3,4'-piperidin]-2-one (CAS 1160248-48-5)
- 1'-Acetyl-6-bromospiro[indoline-3,4'-piperidin]-2-one (CAS 1160248-50-9)
- 5-Bromospiro[benzo[c]fluorene-7,9'-fluorene] (CAS 1175203-78-7)
- 6'-Bromospiro[cyclobutane-1,3'-indolin]-2'-one (CAS 1190861-39-2)
Recommended Standards
- 1-(tert-Butoxycarbonyl)-3-fluoropyrrolidine-3-carboxylic acid (CAS 1001754-59-1)
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- 3-(3,4,5-Trifluorophenyl)-1-propene (CAS 213327-80-1)
- Fulvestrant EP Impurity F (CAS CATO-C4X-19176)
- 5-((4-Chlorophenoxy)methyl)-1,3,4-oxadiazol-2-amine (CAS 21520-97-8)
- rac-(1R,2S,4R,5R,6S)-3-Oxatricyclo[3.2.1.02,4]octane-6-carbonitrile (CAS 21154-35-8)
- Fluticasone Propionate USP Related Compound J (CAS 28416-82-2)
- 2-[(Quinolin-8-yl)amino]-2,3-dihydro-1H-isoindole-1,3-dione (CAS 329763-37-3)
- Procaterol Impurity 6 (CAS CATO-C4X-18106)
- Semaglutide impurity 47 (CAS CATO-C4X-222647)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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